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    Lgals4 galectin 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25474, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lgals4provided by RGD
    Official Full Name
    galectin 4provided by RGD
    Primary source
    RGD:3003
    See related
    EnsemblRapid:ENSRNOG00000020338 AllianceGenome:RGD:3003
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    L-36; L36LBI
    Summary
    Predicted to enable carbohydrate binding activity and galactoside binding activity. Predicted to act upstream of or within antibacterial peptide biosynthetic process. Predicted to be located in extracellular space. Orthologous to human LGALS4 (galectin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 31.5), Liver (RPKM 5.2) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Lgals4 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93248463..93260002)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84124766..84132481)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (87019598..87027720)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene uncharacterized LOC134483092 Neighboring gene uncharacterized LOC102550499 Neighboring gene heterogeneous nuclear ribonucleoprotein L Neighboring gene enoyl-CoA hydratase 1 Neighboring gene galectin 7 Neighboring gene calpain 12

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding  
    enables carbohydrate binding  
    enables galactoside binding  
    Component Evidence Code Pubs
    located_in extracellular space  

    General protein information

    Preferred Names
    galectin-4
    Names
    L-36 lactose-binding protein
    L36LBP
    Lectin, galactose binding, soluble 4 (Galectin-4)
    gal-4
    lactose-binding lectin 4
    lectin, galactoside-binding, soluble, 4 (galectin 4)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012975.2NP_037107.1  galectin-4

      See identical proteins and their annotated locations for NP_037107.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      P38552
      UniProtKB/TrEMBL
      A0A8I6AEZ8, A6J9L5
      Related
      ENSRNOP00000047505.2, ENSRNOT00000041205.4
      Conserved Domains (1) summary
      smart00908
      Location:24148
      Gal-bind_lectin; Galactoside-binding lectin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      93248463..93260002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281850.1XP_063137920.1  galectin-4 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AEZ8
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