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    Ugt2b7 UDP glucuronosyltransferase family 2 member B7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 286989, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ugt2b7provided by RGD
    Official Full Name
    UDP glucuronosyltransferase family 2 member B7provided by RGD
    Primary source
    RGD:708417
    See related
    EnsemblRapid:ENSRNOG00000070682 AllianceGenome:RGD:708417
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ugt2b8; UDPGT 2B7
    Summary
    Predicted to enable glucuronosyltransferase activity. Predicted to be involved in androgen metabolic process; cellular glucuronidation; and estrogen metabolic process. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human UGT2B7 (UDP glucuronosyltransferase family 2 member B7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 10.0), Liver (RPKM 8.3) and 3 other tissues See more
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    Genomic context

    See Ugt2b7 in Genome Data Viewer
    Location:
    14p21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (21251535..21274451)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (20896682..20919604)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (22597103..22619968)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene UDP-glucuronosyltransferase 2 family, member 37 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide B35 Neighboring gene heterogeneous nuclear ribonucleoprotein A3-like Neighboring gene UDP glucuronosyltransferase family 2 member B7 like 1 Neighboring gene peptidylprolyl isomerase A (cyclophilin A)-like 4D

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables glucuronosyltransferase activity  
    enables glucuronosyltransferase activity  
    enables glucuronosyltransferase activity  
    enables glucuronosyltransferase activity  
    NOT enables retinoic acid binding  
    Process Evidence Code Pubs
    involved_in androgen metabolic process  
    involved_in androgen metabolic process  
    involved_in biological_process  
    involved_in cellular glucuronidation  
    involved_in cellular glucuronidation  
    involved_in estrogen metabolic process  
    involved_in estrogen metabolic process  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane  
    located_in membrane  

    General protein information

    Preferred Names
    UDP-glucuronosyltransferase 2B7
    Names
    UDP glucuronosyltransferase 2 family, polypeptide B7
    UDP-glucuronosyltransferase 2B8
    UDPGT 2B8
    UGT2B-RH4
    NP_775445.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173323.2NP_775445.2  UDP-glucuronosyltransferase 2B7 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/Swiss-Prot
      Q62789
      UniProtKB/TrEMBL
      A6JCQ2, F1LLV5
      Related
      ENSRNOP00000050445.5, ENSRNOT00000048482.6
      Conserved Domains (1) summary
      pfam00201
      Location:24527
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      21251535..21274451
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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