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    Atxn10 ataxin 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 170821, updated on 9-Dec-2024

    Summary

    Official Symbol
    Atxn10provided by RGD
    Official Full Name
    ataxin 10provided by RGD
    Primary source
    RGD:621813
    See related
    EnsemblRapid:ENSRNOG00000014637 AllianceGenome:RGD:621813
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Sca10
    Summary
    Enables enzyme binding activity and identical protein binding activity. Predicted to be involved in neuron projection development and regulation of cytokinesis. Predicted to act upstream of or within cilium assembly. Predicted to be located in several cellular components, including microtubule organizing center; midbody; and neuronal cell body. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 10. Orthologous to human ATXN10 (ataxin 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 430.1), Heart (RPKM 338.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Atxn10 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (118321516..118444967)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (116441768..116565093)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (126228416..126351728)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene fibulin 1 Neighboring gene uncharacterized LOC120093703 Neighboring gene uncharacterized LOC120093704 Neighboring gene U2 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA48 Neighboring gene Wnt family member 7B Neighboring gene uncharacterized LOC120093705 Neighboring gene uncharacterized LOC102554082 Neighboring gene uncharacterized LOC134479761

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables enzyme binding PubMed 
    enables identical protein binding PubMed 
    Process Evidence Code Pubs
    involved_in cell division  
    involved_in cilium assembly  
    acts_upstream_of_or_within cilium assembly  
    involved_in nervous system development  
    involved_in neuron projection development  
    involved_in neuron projection development  
    involved_in neuron projection development  
    involved_in neuron projection development  
    involved_in regulation of cytokinesis  
    involved_in regulation of cytokinesis  
    involved_in regulation of cytokinesis  
    Items 1 - 20 of 23
    Component Evidence Code Pubs
    located_in centriole  
    located_in centriole  
    located_in centriole  
    located_in ciliary basal body  
    located_in ciliary basal body  
    located_in ciliary basal body  
    located_in cytoplasm  
    located_in cytoplasm  
    is_active_in cytosol  
    located_in cytosol  
    located_in cytosol  
    located_in dendrite  
    located_in dendrite  
    located_in midbody  
    located_in midbody  
    located_in midbody  
    located_in neuronal cell body  
    located_in neuronal cell body  
    located_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  
    located_in perinuclear region of cytoplasm  
    located_in plasma membrane  
    located_in plasma membrane  
    Items 1 - 20 of 23

    General protein information

    Preferred Names
    ataxin-10
    Names
    ataxin 10 homolog
    neuronal beta-catenin-like protein
    spinocerebellar ataxia 10 homolog
    spinocerebellar ataxia type 10 protein homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133313.2NP_579847.1  ataxin-10

      See identical proteins and their annotated locations for NP_579847.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062087
      UniProtKB/Swiss-Prot
      Q9ER24
      UniProtKB/TrEMBL
      A0A8L2QB12, A6HTE2
      Related
      ENSRNOP00000021071.7, ENSRNOT00000021071.8
      Conserved Domains (1) summary
      pfam09759
      Location:370467
      Atx10homo_assoc; Spinocerebellar ataxia type 10 protein domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      118321516..118444967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262941.1XP_063119011.1  ataxin-10 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZUU4, A0A8L2QB12
      Related
      ENSRNOP00000082915.2, ENSRNOT00000094792.2
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