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    Zfp467 zinc finger protein 467 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500110, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Zfp467provided by RGD
    Official Full Name
    zinc finger protein 467provided by RGD
    Primary source
    RGD:1561603
    See related
    EnsemblRapid:ENSRNOG00000007707 AllianceGenome:RGD:1561603
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf467
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human ZNF467 (zinc finger protein 467). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 39.5), Lung (RPKM 30.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp467 in Genome Data Viewer
    Location:
    4q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (78716473..78725829, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (77385752..77394709, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (78068822..78077962, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486766 Neighboring gene transfer RNA cysteine (anticodon GCA) 28 Neighboring gene KRAB-A domain containing 1 Neighboring gene SCO-spondin Neighboring gene uncharacterized LOC120102263 Neighboring gene zinc finger protein 862

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3. Nakayama K, et al. EMBO J, 2002 Nov 15. PMID 12426389, Free PMC Article
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 467

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024327.1 → NP_001019498.1  zinc finger protein 467

      See identical proteins and their annotated locations for NP_001019498.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086534
      UniProtKB/Swiss-Prot
      Q5RJR4
      UniProtKB/TrEMBL
      A6K0E7
      Related
      ENSRNOP00000010377.4, ENSRNOT00000010377.8
      Conserved Domains (4) summary
      COG5048
      Location:190 → 564
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:218 → 238
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:216 → 238
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:230 → 255
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      78716473..78725829 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017592790.3 → XP_017448279.1  zinc finger protein 467 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K5V9

    2. XM_006236433.5 → XP_006236495.1  zinc finger protein 467 isoform X1

      See identical proteins and their annotated locations for XP_006236495.1

      UniProtKB/Swiss-Prot
      Q5RJR4
      UniProtKB/TrEMBL
      A6K0E7
      Conserved Domains (4) summary
      COG5048
      Location:190 → 564
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:218 → 238
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:216 → 238
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:230 → 255
      zf-H2C2_2; Zinc-finger double domain

    3. XM_006236432.5 → XP_006236494.1  zinc finger protein 467 isoform X1

      See identical proteins and their annotated locations for XP_006236494.1

      UniProtKB/Swiss-Prot
      Q5RJR4
      UniProtKB/TrEMBL
      A6K0E7
      Conserved Domains (4) summary
      COG5048
      Location:190 → 564
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:218 → 238
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:216 → 238
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:230 → 255
      zf-H2C2_2; Zinc-finger double domain

    4. XM_006236434.5 → XP_006236496.1  zinc finger protein 467 isoform X1

      See identical proteins and their annotated locations for XP_006236496.1

      UniProtKB/Swiss-Prot
      Q5RJR4
      UniProtKB/TrEMBL
      A6K0E7
      Conserved Domains (4) summary
      COG5048
      Location:190 → 564
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:218 → 238
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:216 → 238
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:230 → 255
      zf-H2C2_2; Zinc-finger double domain

    5. XM_006236431.5 → XP_006236493.1  zinc finger protein 467 isoform X1

      See identical proteins and their annotated locations for XP_006236493.1

      UniProtKB/Swiss-Prot
      Q5RJR4
      UniProtKB/TrEMBL
      A6K0E7
      Conserved Domains (4) summary
      COG5048
      Location:190 → 564
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:218 → 238
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:216 → 238
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:230 → 255
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5RJR4.1 GenPept UniProtKB/Swiss-Prot:Q5RJR4

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