Dstl1 dystonin like 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dstl1provided by RGD
Official Full Name: dystonin like 1provided by RGD
Primary source: RGD:1587008
See related: EnsemblRapid:ENSRNOG00000023828 AllianceGenome:RGD:1587008
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable actin filament binding activity. Predicted to be involved in actin crosslink formation. Predicted to be located in cytoplasm. Predicted to be active in actin filament. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 100.8), Brain (RPKM 17.8) and 1 other tissue See more
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (109718777..109736508, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (107838089..107847304, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (117180653..117187739, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables actin filament binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in actin crosslink formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule bundle formation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein localization to microtubule plus-end	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of microtubule polymerization or depolymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
colocalizes_with microtubule plus-end	IBA Inferred from Biological aspect of Ancestor more info
colocalizes_with stress fiber	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_063264666.1 → XP_063120736.1 uncharacterized protein Dstl1 isoform X3
XM_002729838.7 → XP_002729884.2 uncharacterized protein Dstl1 isoform X1

See identical proteins and their annotated locations for XP_002729884.2

UniProtKB/TrEMBL

D4ABX7

Related

ENSRNOP00000014191.6, ENSRNOT00000014191.8

Conserved Domains (2) summary

cl02488
Location:157 → 282

SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

cl02524
Location:672 → 700

GAS2; Growth-Arrest-Specific Protein 2 Domain
XM_017595384.3 → XP_017450873.1 uncharacterized protein Dstl1 isoform X2
XM_039080532.2 → XP_038936460.1 uncharacterized protein Dstl1 isoform X4
XM_063264667.1 → XP_063120737.1 uncharacterized protein Dstl1 isoform X5

UniProtKB/TrEMBL

A6HS62