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    Ssc4d scavenger receptor cysteine rich family member with 4 domains [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304401, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Ssc4dprovided by RGD
    Official Full Name
    scavenger receptor cysteine rich family member with 4 domainsprovided by RGD
    Primary source
    RGD:1306970
    See related
    EnsemblRapid:ENSRNOG00000001435 AllianceGenome:RGD:1306970
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Srcrb4d
    Summary
    Predicted to be located in extracellular region and membrane. Orthologous to human SSC4D (scavenger receptor cysteine rich family member with 4 domains). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 42.6), Adrenal (RPKM 30.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ssc4d in Genome Data Viewer
    Location:
    12q12
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (26339576..26361317)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (20702931..20723732)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (23752823..23769466)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene deltex E3 ubiquitin ligase 2 Neighboring gene zona pellucida glycoprotein 3 Neighboring gene U6 spliceosomal RNA Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma Neighboring gene ribosomal protein S11, pseudogene 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    scavenger receptor cysteine-rich domain-containing group B protein
    Names
    scavenger receptor cysteine rich domain containing, group B (4 domains)
    scavenger receptor cysteine rich family, 4 domains

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431720.1 → NP_001418649.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J097, D3ZQH3

    2. NM_001431722.1 → NP_001418651.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J097, D3ZQH3

    3. NM_001431723.1 → NP_001418652.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I6ANW2, A6J099

    4. NM_001431724.1 → NP_001418653.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012

    5. NM_001431725.1 → NP_001418654.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 4

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A0A8I6ANW2, A6J099

    6. NM_001431726.1 → NP_001418655.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J0A0

    7. NM_001431727.1 → NP_001418656.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J0A0

    8. NM_001431728.1 → NP_001418657.1  scavenger receptor cysteine-rich domain-containing group B protein isoform 5

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6J0A0

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      26339576..26361317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090074.2 → XP_038946002.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X5

      Conserved Domains (1) summary
      smart00202
      Location:200 → 299
      SR; Scavenger receptor Cys-rich

    2. XM_017598503.3 → XP_017453992.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X2

      UniProtKB/TrEMBL
      A6J097
      Related
      ENSRNOP00000111627.1, ENSRNOT00000138849.1
      Conserved Domains (2) summary
      smart00202
      Location:200 → 299
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:205 → 300
      SRCR; Scavenger receptor cysteine-rich domain

    3. XM_039090072.2 → XP_038946000.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X1

      Related
      ENSRNOP00000001953.6, ENSRNOT00000001953.8
      Conserved Domains (1) summary
      smart00202
      Location:200 → 299
      SR; Scavenger receptor Cys-rich

    4. XM_017598504.3 → XP_017453993.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X3

      UniProtKB/TrEMBL
      A6J097

    5. XM_063271880.1 → XP_063127950.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X4

    6. XM_017598501.3 → XP_017453990.1  scavenger receptor cysteine-rich domain-containing group B protein isoform X1

      Conserved Domains (1) summary
      smart00202
      Location:200 → 299
      SR; Scavenger receptor Cys-rich
    Nucleotide Protein Strain
    Heading Accession and Version

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