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    Cldn17 claudin 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304125, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cldn17provided by RGD
    Official Full Name
    claudin 17provided by RGD
    Primary source
    RGD:1307462
    See related
    AllianceGenome:RGD:1307462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable channel activity and paracellular tight junction channel activity. Predicted to be involved in bicellular tight junction assembly; cell adhesion; and paracellular transport. Predicted to be located in tight junction. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN17 (claudin 17). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cldn17 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (41313675..41314851, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (27827454..27828630, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (28477184..28478360, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene glutamate ionotropic receptor kainate type subunit 1 Neighboring gene sorting nexin-1-like Neighboring gene uncharacterized LOC108352301 Neighboring gene KAT8 regulatory NSL complex subunit 2, pseudogene 1 Neighboring gene claudin 8

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables paracellular tight junction channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in paracellular transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in tight junction ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107112.1NP_001100582.1  claudin-17

      See identical proteins and their annotated locations for NP_001100582.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473989
      UniProtKB/TrEMBL
      A6JL93, D4A6L7
      Conserved Domains (1) summary
      cl21598
      Location:6182
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      41313675..41314851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)