Tmem147 transmembrane protein 147 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tmem147provided by RGD
Official Full Name: transmembrane protein 147provided by RGD
Primary source: RGD:1304706
See related: EnsemblRapid:ENSRNOG00000021006 AllianceGenome:RGD:1304706
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1304706
Summary: Predicted to enable ribosome binding activity. Predicted to be involved in multi-pass transmembrane protein insertion into ER membrane and protein localization to nuclear inner membrane. Predicted to be located in nuclear membrane and plasma membrane. Predicted to be part of multi-pass translocon complex. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMEM147 (transmembrane protein 147). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 292.8), Heart (RPKM 231.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 1q21

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (95104448..95106268, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (85977028..85978848, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (89177995..89179815, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ribosome binding	IEA Inferred from Electronic Annotation more info
enables ribosome binding	ISO Inferred from Sequence Orthology more info
enables ribosome binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in multi-pass transmembrane protein insertion into ER membrane	IEA Inferred from Electronic Annotation more info
involved_in multi-pass transmembrane protein insertion into ER membrane	ISO Inferred from Sequence Orthology more info
involved_in multi-pass transmembrane protein insertion into ER membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization to nuclear inner membrane	IEA Inferred from Electronic Annotation more info
involved_in protein localization to nuclear inner membrane	ISO Inferred from Sequence Orthology more info
involved_in protein localization to nuclear inner membrane	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of multi-pass translocon complex	IEA Inferred from Electronic Annotation more info
part_of multi-pass translocon complex	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	IEA Inferred from Electronic Annotation more info
located_in nuclear membrane	ISO Inferred from Sequence Orthology more info
located_in nuclear membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: BOS complex subunit TMEM147

Names: seven transmembrane domain protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.