S100z S100 calcium binding protein Z [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: S100zprovided by RGD
Official Full Name: S100 calcium binding protein Zprovided by RGD
Primary source: RGD:1562902
See related: EnsemblRapid:ENSRNOG00000078837 AllianceGenome:RGD:1562902
Gene type: protein coding
RefSeq status: INFERRED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562902
Summary: Predicted to enable calcium ion binding activity; calcium-dependent protein binding activity; and protein homodimerization activity. Orthologous to human S100Z (S100 calcium binding protein Z). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 5.2), Kidney (RPKM 0.8) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (28472527..28476750, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (26737796..26753611, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (25188381..25203627, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	ISO Inferred from Sequence Orthology more info
enables calcium-dependent protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein S100-Z

Names: S100 calcium binding protein, zeta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191701.2 → NP_001178630.1 protein S100-Z

See identical proteins and their annotated locations for NP_001178630.1

Status: INFERRED

Source sequence(s)

JAXUCZ010000002

UniProtKB/TrEMBL

D3ZEJ4

Related

ENSRNOP00000101640.1, ENSRNOT00000142490.1

Conserved Domains (1) summary

cl08302
Location:1 → 93

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...