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    Art4 ADP-ribosyltransferase 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312806, updated on 9-Dec-2024

    Summary

    Official Symbol
    Art4provided by RGD
    Official Full Name
    ADP-ribosyltransferase 4provided by RGD
    Primary source
    RGD:1306456
    See related
    EnsemblRapid:ENSRNOG00000005670 AllianceGenome:RGD:1306456
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ATR4
    Summary
    Predicted to enable NAD+-protein poly-ADP-ribosyltransferase activity. Orthologous to human ART4 (ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 130.5), Thymus (RPKM 130.4) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Art4 in Genome Data Viewer
    Location:
    4q43
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (171468415..171482435, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (169740331..169751571, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (170830851..170841187, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene WW domain binding protein 11 Neighboring gene single-pass membrane protein with coiled-coil domains 3 like 1 Neighboring gene sorbitol dehydrogenase-like Neighboring gene similar to human chromosome 12 open reading frame 60 Neighboring gene single-pass membrane protein with coiled-coil domains 3 Neighboring gene matrix Gla protein Neighboring gene endoplasmic reticulum protein 27

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    ecto-ADP-ribosyltransferase 4
    Names
    ADP-ribosyltransferase 4 (Dombrock blood group)
    NAD(P)(+)--arginine ADP-ribosyltransferase
    NP_001166980.1
    XP_038963627.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173509.1NP_001166980.1  ecto-ADP-ribosyltransferase 4 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A6IMI9, F1MA10
      Related
      ENSRNOP00000007485.4, ENSRNOT00000007485.7
      Conserved Domains (1) summary
      cl00173
      Location:41261
      VIP2; VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      171468415..171482435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039107699.2XP_038963627.1  ecto-ADP-ribosyltransferase 4 isoform X1

      UniProtKB/TrEMBL
      A6IMI9
      Conserved Domains (1) summary
      cl00173
      Location:37257
      VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of ...