Slc41a3 solute carrier family 41, member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Slc41a3provided by RGD
Full Name: solute carrier family 41, member 3provided by RGD
Primary source: RGD:1589573
See related: EnsemblRapid:ENSRNOG00000045821 AllianceGenome:RGD:1589573
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable magnesium:sodium antiporter activity. Predicted to be involved in mitochondrial magnesium ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in plasma membrane. Orthologous to human SLC41A3 (solute carrier family 41 member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 137.9), Adrenal (RPKM 137.1) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q34

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (124666789..124711968)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (123109555..123154766)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (123467552..123513447, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH133572 (e-PCR)
- UniSTS:216855

AU048745 (e-PCR)
- UniSTS:145195

D4Rat48 (e-PCR)
- UniSTS:118841

D4Got82 (e-PCR)
- UniSTS:112994

Slc41a3 (e-PCR), detects polymorphism
- UniSTS:527551

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables inorganic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables magnesium:sodium antiporter activity	ISO Inferred from Sequence Orthology more info
enables magnesium:sodium antiporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in magnesium ion transport	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial magnesium ion transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial magnesium ion transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in monoatomic cation transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in sodium ion transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 41 member 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.