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    Cntnap5a contactin associated protein-like 5A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297832, updated on 9-Dec-2024

    Summary

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    Symbol
    Cntnap5aprovided by RGD
    Full Name
    contactin associated protein-like 5Aprovided by RGD
    Primary source
    RGD:1559812
    See related
    EnsemblRapid:ENSRNOG00000070614 AllianceGenome:RGD:1559812
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Caspr5-1; RGD1559812
    Summary
    Predicted to be involved in cell adhesion. Predicted to be located in membrane. Orthologous to human CNTNAP5 (contactin associated protein family member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 54.3) See more
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    Genomic context

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    See Cntnap5a in Genome Data Viewer
    Location:
    13p13
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (8968048..9976147)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (8960951..9962906)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (79860..841474)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene FERM domain containing 3, pseudogene 1 Neighboring gene uncharacterized LOC108352511 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene selenoprotein K, pseudogene 2 Neighboring gene myosin light polypeptide 6-like Neighboring gene mitogen-activated protein kinase 1 interacting protein 1 like 2 Neighboring gene uncharacterized LOC134481613

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. New members of the neurexin superfamily: multiple rodent homologues of the human CASPR5 gene. Traut W, et al. Mamm Genome, 2006 Jul. PMID 16845472

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    contactin-associated protein like 5-1
    Names
    cell recognition molecule Caspr5-1
    cell recognition molecule Caspr5a
    contactin-associated protein like 5-1-like
    contactin-associated protein-like 5a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001047865.2 → NP_001041330.1  contactin-associated protein like 5-1 precursor

      See identical proteins and their annotated locations for NP_001041330.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013
      UniProtKB/Swiss-Prot
      Q0V8T6
      UniProtKB/TrEMBL
      A0A8I6G6R0
      Related
      ENSRNOP00000076029.2, ENSRNOT00000092965.3
      Conserved Domains (5) summary
      smart00231
      Location:39 → 174
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain
      cd00057
      Location:42 → 173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:792 → 936
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:550 → 581
      EGF; EGF-like domain
      pfam02210
      Location:395 → 521
      Laminin_G_2; Laminin G domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      8968048..9976147
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090650.2 → XP_038946578.1  contactin-associated protein like 5-1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6G6R0
      Related
      ENSRNOP00000095092.2, ENSRNOT00000111316.2
      Conserved Domains (4) summary
      cd00057
      Location:42 → 173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:793 → 937
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:551 → 582
      EGF; EGF-like domain
      pfam02210
      Location:209 → 338
      Laminin_G_2; Laminin G domain

    2. XM_039090651.2 → XP_038946579.1  contactin-associated protein like 5-1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6G6R0
      Related
      ENSRNOP00000087083.2, ENSRNOT00000104126.2
      Conserved Domains (4) summary
      cd00057
      Location:42 → 173
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      cd00110
      Location:793 → 937
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam00008
      Location:551 → 582
      EGF; EGF-like domain
      pfam02210
      Location:209 → 338
      Laminin_G_2; Laminin G domain

    RNA

    1. XR_005492234.2 RNA Sequence

    2. XR_005492233.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0V8T6.1 GenPept UniProtKB/Swiss-Prot:Q0V8T6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials