Rpl-1 chorionic somatomammotropin hormone 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Gene symbol: Rpl-1
Gene description: chorionic somatomammotropin hormone 1
See related: EnsemblRapid:ENSRNOG00000074382
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Pl1; Csh1; Pl-I; Pl-Im; Rhco1; rPL-I; Prl3d1
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 17p12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (38041402..38047329, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (39777255..39782877, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

lactogens mediating their protective effect through the JAK2/STAT5 pathway in the beta cell and through Bcl-XL in any cell type.
Title: Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.
Differentiation in hypoxia also blocked the induction of CSH1 protein.
Title: Hypoxia inhibits differentiation of lineage-specific Rcho-1 trophoblast giant cells.

Submit: New GeneRIF Correction

General protein information

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Preferred Names: chorionic somatomammotropin hormone 1

Names: Placental lactogen I; Prolactin-3D1; lactogen I; placental lactogen 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_017363.3 → NP_059059.3 chorionic somatomammotropin hormone 1 precursor

Status: VALIDATED

Source sequence(s)

FQ230119

UniProtKB/TrEMBL

A6J7T3

Related

ENSRNOP00000108787.1, ENSRNOT00000131042.1

Conserved Domains (1) summary

cd10288
Location:35 → 224

prolactin_like; Prolactin (PRL or PRL1), chorionic somatomammotropin, and related pituitary gland hormones