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    Epop elongin BC and polycomb repressive complex 2 associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691153, updated on 9-Dec-2024

    Summary

    Official Symbol
    Epopprovided by RGD
    Official Full Name
    elongin BC and polycomb repressive complex 2 associated proteinprovided by RGD
    Primary source
    RGD:1587434
    See related
    EnsemblRapid:ENSRNOG00000048187 AllianceGenome:RGD:1587434
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including neuron fate commitment; regulation of transcription by RNA polymerase II; and transcription elongation-coupled chromatin remodeling. Predicted to be part of ESC/E(Z) complex and elongin complex. Orthologous to human EPOP (elongin BC and polycomb repressive complex 2 associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Epop in Genome Data Viewer
    Location:
    10q31
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (83120767..83122287, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (82624392..82625912, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (85573369..85574889, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene SRC kinase signaling inhibitor 1 Neighboring gene uncharacterized LOC102548331 Neighboring gene uncharacterized LOC134480715 Neighboring gene uncharacterized LOC120095289 Neighboring gene MLLT6, PHD finger containing Neighboring gene CDGSH iron sulfur domain 3

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in neuron fate commitment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within neuron fate commitment ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in stem cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription elongation-coupled chromatin remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of ESC/E(Z) complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of elongin complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    elongin BC and Polycomb repressive complex 2-associated protein
    Names
    uncharacterized protein C17orf96 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109627.1NP_001103097.1  elongin BC and Polycomb repressive complex 2-associated protein

      See identical proteins and their annotated locations for NP_001103097.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473948
      UniProtKB/TrEMBL
      A6HIL0, M0RD31
      Related
      ENSRNOP00000067524.1, ENSRNOT00000072274.4
      Conserved Domains (1) summary
      pfam15223
      Location:297359
      DUF4584; Domain of unknown function (DUF4584)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      83120767..83122287 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)