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    Lrrc74a leucine rich repeat containing 74A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314328, updated on 9-Dec-2024

    Summary

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    Symbol
    Lrrc74aprovided by RGD
    Full Name
    leucine rich repeat containing 74Aprovided by RGD
    Primary source
    RGD:1564488
    See related
    EnsemblRapid:ENSRNOG00000052456 AllianceGenome:RGD:1564488
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Lrrc74
    Summary
    Orthologous to human LRRC74A (leucine rich repeat containing 74A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 227.6) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc74a in Genome Data Viewer
    Location:
    6q31
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (112117226..112147152)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (106386276..106417112)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (110681551..110776904)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene vasohibin 1 Neighboring gene angel homolog 1 Neighboring gene uncharacterized LOC108351370 Neighboring gene uncharacterized LOC134479453

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114373, MGC156476

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 74A
    Names
    leucine rich repeat containing 74
    leucine-rich repeat-containing protein 74
    uncharacterized protein C14orf166B homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037783.2 → NP_001032872.2  leucine-rich repeat-containing protein 74A

      See identical proteins and their annotated locations for NP_001032872.2

      Status: VALIDATED

      Source sequence(s)
      BC127444, CR475527, JAXUCZ010000006
      UniProtKB/Swiss-Prot
      A0JPI9, Q4KLZ5
      Related
      ENSRNOP00000086029.1, ENSRNOT00000098897.2
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:91 → 353
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      112117226..112147152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112315.2 → XP_038968243.1  leucine-rich repeat-containing protein 74A isoform X3

      UniProtKB/TrEMBL
      A0A0G2JWD4
      Conserved Domains (2) summary
      sd00034
      Location:148 → 176
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl39015
      Location:91 → 331
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_039112314.2 → XP_038968242.1  leucine-rich repeat-containing protein 74A isoform X2

      Conserved Domains (2) summary
      sd00033
      Location:113 → 140
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:81 → 317
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_039112313.2 → XP_038968241.1  leucine-rich repeat-containing protein 74A isoform X1

      UniProtKB/TrEMBL
      A0A8I6A2M8
      Related
      ENSRNOP00000085143.1, ENSRNOT00000118016.2
      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:91 → 353
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_039112316.2 → XP_038968244.1  leucine-rich repeat-containing protein 74A isoform X4

      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:91 → 320
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_039112318.2 → XP_038968246.1  leucine-rich repeat-containing protein 74A isoform X6

      Conserved Domains (2) summary
      sd00033
      Location:148 → 176
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:91 → 320
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    6. XM_039112319.2 → XP_038968247.1  leucine-rich repeat-containing protein 74A isoform X7

      Conserved Domains (2) summary
      sd00031
      Location:142 → 176
      LRR_1; leucine-rich repeat [structural motif]
      cl39015
      Location:86 → 227
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    7. XM_063261945.1 → XP_063118015.1  leucine-rich repeat-containing protein 74A isoform X7

    8. XM_063261946.1 → XP_063118016.1  leucine-rich repeat-containing protein 74A isoform X8

    9. XM_063261947.1 → XP_063118017.1  leucine-rich repeat-containing protein 74A isoform X9

    10. XM_039112325.2 → XP_038968253.1  leucine-rich repeat-containing protein 74A isoform X9

      Conserved Domains (1) summary
      cl39015
      Location:86 → 184
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    11. XM_039112317.2 → XP_038968245.1  leucine-rich repeat-containing protein 74A isoform X5

      Conserved Domains (2) summary
      sd00033
      Location:11 → 38
      LRR_RI; leucine-rich repeat [structural motif]
      cl39015
      Location:13 → 244
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0JPI9.1 GenPept UniProtKB/Swiss-Prot:A0JPI9

    Gene LinkOut

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