Ly6g6c lymphocyte antigen 6 family member G6C [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ly6g6cprovided by RGD
Official Full Name: lymphocyte antigen 6 family member G6Cprovided by RGD
Primary source: RGD:1302999
See related: EnsemblRapid:ENSRNOG00000070605 AllianceGenome:RGD:1302999
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable identical protein binding activity. Predicted to act upstream of or within response to bacterium. Predicted to be part of protein-containing complex. Predicted to colocalize with external side of plasma membrane. Orthologous to human LY6G6C (lymphocyte antigen 6 family member G6C). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 55.7), Lung (RPKM 19.6) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (3758290..3760987, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (3753632..3757205, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (5056851..5060398)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to bacterium	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
colocalizes_with external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in external side of plasma membrane	ISO Inferred from Sequence Orthology more info
part_of protein-containing complex	IBA Inferred from Biological aspect of Ancestor more info
part_of protein-containing complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: lymphocyte antigen 6 complex locus protein G6c

Names: lymphocyte antigen 6 complex G6C; lymphocyte antigen 6 complex, locus G6C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001969.1 → NP_001001969.1 lymphocyte antigen 6 complex locus protein G6c precursor

See identical proteins and their annotated locations for NP_001001969.1

Status: VALIDATED

Source sequence(s)

BX883045

UniProtKB/TrEMBL

A0A8I6AS77, A6KTS4, D3ZX79

Related

ENSRNOP00000001119.4, ENSRNOT00000001119.7

Conserved Domains (1) summary

cl10471
Location:22 → 103

LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...