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    Capsl calcyphosine-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294795, updated on 9-Dec-2024

    Summary

    Official Symbol
    Capslprovided by RGD
    Official Full Name
    calcyphosine-likeprovided by RGD
    Primary source
    RGD:1308776
    See related
    EnsemblRapid:ENSRNOG00000054277 AllianceGenome:RGD:1308776
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308776
    Summary
    Predicted to enable calcium ion binding activity. Orthologous to human CAPSL (calcyphosine like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 39.5), Brain (RPKM 7.7) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Capsl in Genome Data Viewer
    Location:
    2q16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (60122162..60152692)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (58394995..58425527)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (58724855..58755220)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene UDP glycosyltransferase family 3 member A1 Neighboring gene UDP glycosyltransferase 3 family, polypeptide A2, pseudogene 1 Neighboring gene interleukin 7 receptor Neighboring gene E3 SUMO-protein ligase KIAA1586-like Neighboring gene sperm flagellar 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106417.1NP_001099887.1  calcyphosin-like protein

      See identical proteins and their annotated locations for NP_001099887.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474048
      UniProtKB/TrEMBL
      A6KGJ8, D4A6W9
      Related
      ENSRNOP00000074768.1, ENSRNOT00000089609.3
      Conserved Domains (3) summary
      cd00051
      Location:46105
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd15898
      Location:4672
      EFh_PI-PLC; EF-hand motif [structural motif]
      cl28895
      Location:46184
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      60122162..60152692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008760763.4XP_008758985.1  calcyphosin-like protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6GHT1
      Related
      ENSRNOP00000089108.1, ENSRNOT00000101019.2
      Conserved Domains (3) summary
      cd00051
      Location:46105
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:80140
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:116182
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...