U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Stk31 serine threonine kinase 31 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500120, updated on 4-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    Stk31provided by RGD
    Official Full Name
    serine threonine kinase 31provided by RGD
    Primary source
    RGD:1564384
    See related
    EnsemblRapid:ENSRNOG00000057554 AllianceGenome:RGD:1564384
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564384
    Summary
    Predicted to enable protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in acrosomal vesicle. Orthologous to human STK31 (serine/threonine kinase 31). [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Restricted expression toward (RPKM 127.1) See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Stk31 in Genome Data Viewer
    Location:
    4q24
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (79701470..79797085)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (78370691..78467599)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (79055493..79153849)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 221, member A Neighboring gene ribosomal protein S11 like 1 Neighboring gene uncharacterized LOC120102266 Neighboring gene uncharacterized LOC120102267

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. STK31(TDRD8) is dynamically regulated throughout mouse spermatogenesis and interacts with MIWI protein. Bao J, et al. Histochem Cell Biol, 2012 Mar. PMID 22205278
    2. Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L. Zhou J, et al. Hum Mol Genet, 2015 Nov 15. PMID 26362258, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in acrosomal vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase 31
    NP_001178900.1
    XP_038964060.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191971.1 → NP_001178900.1  serine/threonine-protein kinase 31

      See identical proteins and their annotated locations for NP_001178900.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A8I5ZLI1, A0A8I6AF45
      Related
      ENSRNOP00000078757.1, ENSRNOT00000105358.2
      Conserved Domains (3) summary
      cd04508
      Location:89 → 129
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:29 → 147
      TUDOR; Tudor domain
      cl21453
      Location:803 → 922
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      79701470..79797085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108132.2 → XP_038964060.1  serine/threonine-protein kinase 31 isoform X1

      UniProtKB/TrEMBL
      A0A0G2JWJ2, A0A8I5ZLI1
      Related
      ENSRNOP00000069902.2, ENSRNOT00000086307.3
      Conserved Domains (3) summary
      COG0419
      Location:301 → 696
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      cd20430
      Location:65 → 139
      Tudor_TDRD8; Tudor domain found in Tudor domain-containing protein 8 (TDRD8) and similar proteins
      cl21453
      Location:807 → 926
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools