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    P2rx5 purinergic receptor P2X 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 113995, updated on 9-Dec-2024

    Summary

    Official Symbol
    P2rx5provided by RGD
    Official Full Name
    purinergic receptor P2X 5provided by RGD
    Primary source
    RGD:620256
    See related
    EnsemblRapid:ENSRNOG00000019208 AllianceGenome:RGD:620256
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    P2x5
    Summary
    Enables ATP binding activity; identical protein binding activity; and monoatomic ion channel activity. Involved in several processes, including positive regulation of calcium ion import across plasma membrane; regulation of skeletal muscle tissue regeneration; and response to ATP. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Orthologous to human P2RX5 (purinergic receptor P2X 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 101.3), Muscle (RPKM 42.8) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See P2rx5 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (58276329..58291108)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (57777737..57789426)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (59725438..59737126)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 2-like Neighboring gene uncharacterized LOC108352105 Neighboring gene ER membrane protein complex subunit 6 Neighboring gene Tax1 binding protein 3

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in postsynapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    P2X purinoceptor 5
    Names
    ATP receptor
    purinergic receptor P2X, ligand-gated ion channel, 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080780.3NP_542958.3  P2X purinoceptor 5

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/Swiss-Prot
      A6HGI1, G3V8I0, P51578, Q64613
      Related
      ENSRNOP00000026156.2, ENSRNOT00000026156.7
      Conserved Domains (1) summary
      TIGR00863
      Location:1373
      P2X; cation transporter protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      58276329..58291108
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006246566.5XP_006246628.1  P2X purinoceptor 5 isoform X1

      Related
      ENSRNOP00000111027.1, ENSRNOT00000126428.1
      Conserved Domains (1) summary
      TIGR00863
      Location:1349
      P2X; cation transporter protein
    2. XM_063268265.1XP_063124335.1  P2X purinoceptor 5 isoform X2