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    Gypc glycophorin C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364837, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gypcprovided by RGD
    Official Full Name
    glycophorin Cprovided by RGD
    Primary source
    RGD:1310295
    See related
    AllianceGenome:RGD:1310295
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    GPC
    Summary
    Predicted to be located in plasma membrane. Predicted to be active in cortical cytoskeleton and membrane. Human ortholog(s) of this gene implicated in malaria. Orthologous to human GYPC (glycophorin C (Gerbich blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 104.3), Heart (RPKM 80.0) and 7 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gypc in Genome Data Viewer
    Location:
    18p12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (24434921..24467592, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (24160738..24193408, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (25312386..25344614, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene POTE ankyrin domain family, member F Neighboring gene bridging integrator 1 Neighboring gene uncharacterized LOC120098229 Neighboring gene testis expressed 51 Neighboring gene uncharacterized LOC120098297 Neighboring gene uncharacterized LOC120098296 Neighboring gene large ribosomal subunit protein eL19-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC124900

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cortical cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cortical cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glycophorin-C
    Names
    glycophorin C (Gerbich blood group)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013233.1NP_001013251.1  glycophorin-C

      See identical proteins and their annotated locations for NP_001013251.1

      Status: PROVISIONAL

      Source sequence(s)
      AY234182
      UniProtKB/Swiss-Prot
      Q6XFR6
      UniProtKB/TrEMBL
      A0A8I5ZMD3
      Conserved Domains (1) summary
      smart00294
      Location:4765
      4.1m; putative band 4.1 homologues' binding motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      24434921..24467592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)