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    Cdca7 cell division cycle associated 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311742, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cdca7provided by RGD
    Official Full Name
    cell division cycle associated 7provided by RGD
    Primary source
    RGD:1309363
    See related
    EnsemblRapid:ENSRNOG00000001514 AllianceGenome:RGD:1309363
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in apoptotic process and regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of cell population proliferation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency-centromeric instability-facial anomalies syndrome 3. Orthologous to human CDCA7 (cell division cycle associated 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 305.9), Spleen (RPKM 80.1) and 3 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cdca7 in Genome Data Viewer
    Location:
    3q23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (77730315..77740950)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (57322718..57333353)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (59153281..59163916)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120101564 Neighboring gene mitogen-activated protein kinase kinase kinase 20 Neighboring gene uncharacterized LOC134486106 Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene ribosomal protein S13, pseudogene 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112656

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cell division cycle-associated protein 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025693.1NP_001020864.1  cell division cycle-associated protein 7

      See identical proteins and their annotated locations for NP_001020864.1

      Status: PROVISIONAL

      Source sequence(s)
      BC098690
      UniProtKB/Swiss-Prot
      Q4KM91
      UniProtKB/TrEMBL
      A0A8L2UHI2, A6HM74
      Related
      ENSRNOP00000099715.1, ENSRNOT00000164927.1
      Conserved Domains (1) summary
      pfam10497
      Location:268366
      zf-4CXXC_R1; Zinc-finger domain of monoamine-oxidase A repressor R1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      77730315..77740950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283912.1XP_063139982.1  cell division cycle-associated protein 7 isoform X1

      UniProtKB/TrEMBL
      A0A8L2UHI2