Bcl2l15 Bcl2-like 15 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bcl2l15provided by RGD
Official Full Name: Bcl2-like 15provided by RGD
Primary source: RGD:1562344
See related: EnsemblRapid:ENSRNOG00000037149 AllianceGenome:RGD:1562344
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1562344
Summary: Predicted to be involved in regulation of apoptotic process. Predicted to be active in cytosol and nucleus. Orthologous to human BCL2L15 (BCL2 like 15). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 11.6), Thymus (RPKM 5.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q34

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (194019158..194032516)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (191338959..191344078)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (206307778..206319662)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in regulation of apoptotic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: bcl-2-like protein 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106459.1 → NP_001099929.1 bcl-2-like protein 15

See identical proteins and their annotated locations for NP_001099929.1

Status: PROVISIONAL

Source sequence(s)

CH474015

UniProtKB/TrEMBL

A6K3N0, A6K3N1, D4A1Q8

Related

ENSRNOP00000052920.2, ENSRNOT00000056068.4

Conserved Domains (1) summary

cl02575
Location:114 → 161

Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...