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    Gatd3a glutamine amidotransferase class 1 domain containing 3A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gatd3aprovided by RGD
    Official Full Name
    glutamine amidotransferase class 1 domain containing 3Aprovided by RGD
    Primary source
    RGD:1303003
    See related
    EnsemblRapid:ENSRNOG00000001211 AllianceGenome:RGD:1303003
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    ES1; C21orf33; RGD1303003
    Summary
    Predicted to be active in mitochondrion. Orthologous to human GATD3 (glutamine amidotransferase class 1 domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1682.4), Muscle (RPKM 973.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gatd3a in Genome Data Viewer
    Location:
    20p12
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (10514459..10522556)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (10514793..10522894)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (11244353..11252450)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit 10 Neighboring gene PWP2, small subunit processome component Neighboring gene uncharacterized LOC134483782 Neighboring gene inducible T-cell co-stimulator ligand

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A two-dimensional electrophoresis database of rat heart proteins. Li XP, et al. Electrophoresis, 1999 Apr-May. PMID 10344264
    2. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
    3. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    4. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94888

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ES1 protein homolog, mitochondrial
    Names
    glutamine amidotransferase like class 1 domain containing 3A
    homolog of zebrafish ES1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004225.1 → NP_001004225.1  ES1 protein homolog, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001004225.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079380
      UniProtKB/Swiss-Prot
      P56571, Q68FS5
      UniProtKB/TrEMBL
      A6JK42
      Related
      ENSRNOP00000001609.5, ENSRNOT00000001609.6
      Conserved Domains (1) summary
      cd03133
      Location:43 → 264
      GATase1_ES1; Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      10514459..10522556
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P56571.2 GenPept UniProtKB/Swiss-Prot:P56571

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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