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    Lrrc49 leucine rich repeat containing 49 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300763, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc49provided by RGD
    Official Full Name
    leucine rich repeat containing 49provided by RGD
    Primary source
    RGD:1309466
    See related
    EnsemblRapid:ENSRNOG00000012015 AllianceGenome:RGD:1309466
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309466
    Summary
    Predicted to be located in centriolar satellite. Orthologous to human LRRC49 (leucine rich repeat containing 49). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 216.0), Testes (RPKM 78.2) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrrc49 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (69948962..70056579, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (61053264..61160695, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (65481584..65587687, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene thrombospondin type 1 domain containing 4 Neighboring gene uncharacterized LOC120094180 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC108351719 Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene La ribonucleoprotein 6, translational regulator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 49

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134469.1 → NP_001127941.1  leucine-rich repeat-containing protein 49

      See identical proteins and their annotated locations for NP_001127941.1

      Status: PROVISIONAL

      Source sequence(s)
      BC160848
      UniProtKB/TrEMBL
      A0A8I5ZJG3, B1H239
      Related
      ENSRNOP00000105989.1, ENSRNOT00000132362.1
      Conserved Domains (3) summary
      sd00033
      Location:114 → 135
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:156 → 198
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:202 → 256
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      69948962..70056579 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265149.1 → XP_063121219.1  leucine-rich repeat-containing protein 49 isoform X7

      UniProtKB/TrEMBL
      A0A8I5ZJG3

    2. XM_063265147.1 → XP_063121217.1  leucine-rich repeat-containing protein 49 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZJG3
      Related
      ENSRNOP00000077361.2, ENSRNOT00000119955.2

    3. XM_063265145.1 → XP_063121215.1  leucine-rich repeat-containing protein 49 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZJG3

    4. XM_063265143.1 → XP_063121213.1  leucine-rich repeat-containing protein 49 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZJG3, F7FG58
      Related
      ENSRNOP00000016491.4, ENSRNOT00000016491.6

    5. XM_063265146.1 → XP_063121216.1  leucine-rich repeat-containing protein 49 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZJG3
      Related
      ENSRNOP00000097055.2, ENSRNOT00000109644.2

    6. XM_063265144.1 → XP_063121214.1  leucine-rich repeat-containing protein 49 isoform X2

      UniProtKB/TrEMBL
      A0A0G2K8U5, A0A8I5ZJG3
      Related
      ENSRNOP00000074741.2, ENSRNOT00000091982.3

    7. XM_063265148.1 → XP_063121218.1  leucine-rich repeat-containing protein 49 isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZJG3

    8. XM_063265150.1 → XP_063121220.1  leucine-rich repeat-containing protein 49 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AQS1

    9. XM_063265151.1 → XP_063121221.1  leucine-rich repeat-containing protein 49 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AQS1

    10. XM_063265152.1 → XP_063121222.1  leucine-rich repeat-containing protein 49 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AQS1
    Nucleotide Protein Strain
    Heading Accession and Version

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