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    Maip1 matrix AAA peptidase interacting protein 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301418, updated on 9-Dec-2024

    Summary

    Official Symbol
    Maip1provided by RGD
    Official Full Name
    matrix AAA peptidase interacting protein 1provided by RGD
    Primary source
    RGD:1303159
    See related
    EnsemblRapid:ENSRNOG00000015983 AllianceGenome:RGD:1303159
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable ribosome binding activity. Predicted to be involved in calcium import into the mitochondrion; mitochondrial calcium ion homeostasis; and protein insertion into mitochondrial inner membrane from matrix. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrial inner membrane. Orthologous to human MAIP1 (matrix AAA peptidase interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 177.3), Muscle (RPKM 164.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Maip1 in Genome Data Viewer
    Location:
    9q31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (66473159..66481089)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (58978901..58986831)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (64095978..64103908)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094688 Neighboring gene uncharacterized LOC102549484 Neighboring gene similar to human chromosome 2 open reading frame 69 Neighboring gene tRNA-yW synthesizing protein 5 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ribosomal protein L6, pseudogene 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC94335

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ribosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in calcium import into the mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in calcium import into the mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial calcium ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial calcium ion homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein insertion into mitochondrial inner membrane from matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein insertion into mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein insertion into mitochondrial membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    m-AAA protease-interacting protein 1, mitochondrial
    Names
    uncharacterized protein C2orf47 homolog, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004251.1NP_001004251.1  m-AAA protease-interacting protein 1, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001004251.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079246
      UniProtKB/Swiss-Prot
      Q6AY04
      UniProtKB/TrEMBL
      A0A8I6GEE0, A6IP39
      Related
      ENSRNOP00000021533.5, ENSRNOT00000021533.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      66473159..66481089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)