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    B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367384, updated on 9-Dec-2024

    Summary

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    Symbol
    B3gntl1provided by RGD
    Full Name
    UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1provided by RGD
    Primary source
    RGD:1359497
    See related
    EnsemblRapid:ENSRNOG00000049724 AllianceGenome:RGD:1359497
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    QTGAL
    Summary
    Enables tRNA-queuosine(34) galactosyltransferase activity. Involved in tRNA modification. Predicted to be active in cytoplasm. Orthologous to human B3GNTL1 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 64.4), Thymus (RPKM 56.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See B3gntl1 in Genome Data Viewer
    Location:
    10q32.3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (107363036..107431988, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (106870237..106933723, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (110799409..110863075, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene fructosamine 3 kinase Neighboring gene tubulin folding cofactor D Neighboring gene zinc finger protein 750 Neighboring gene uncharacterized LOC134480642 Neighboring gene uncharacterized LOC134480728

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Zhao X, et al. Cell, 2023 Dec 7. PMID 37992713
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC124891

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA-queuosine(34) galactosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tRNA-queuosine(34) galactosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of translation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in tRNA modification IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in tRNA modification ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    queuosine-tRNA galactosyltransferase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1
    Names
    BGnT-like protein 1
    beta1,3-N-acetylglucosaminyltransferase-like protein 1
    beta3Gn-T-like protein 1
    beta3GnTL1
    NP_001015035.1
    XP_038942442.1
    XP_038942443.1
    XP_038942444.1
    XP_038942446.1
    XP_063125620.1
    XP_063125621.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015035.1 → NP_001015035.1  queuosine-tRNA galactosyltransferase

      See identical proteins and their annotated locations for NP_001015035.1

      Status: PROVISIONAL

      Source sequence(s)
      AY634365
      UniProtKB/Swiss-Prot
      Q2NKP4, Q6GV29
      UniProtKB/TrEMBL
      A0A8I5ZS74
      Related
      ENSRNOP00000064695.2, ENSRNOT00000071141.4
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      107363036..107431988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063269550.1 → XP_063125620.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZS74

    2. XM_039086516.2 → XP_038942444.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZS74
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    3. XM_039086514.2 → XP_038942442.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZS74
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    4. XM_039086515.2 → XP_038942443.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZS74
      Related
      ENSRNOP00000081528.1, ENSRNOT00000103778.2
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    5. XM_063269551.1 → XP_063125621.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q2NKP4, Q6GV29
      UniProtKB/TrEMBL
      A0A8I5ZS74

    6. XM_039086518.2 → XP_038942446.1  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X3

      UniProtKB/Swiss-Prot
      Q2NKP4, Q6GV29
      UniProtKB/TrEMBL
      A0A8I5ZS74
      Conserved Domains (1) summary
      cd06913
      Location:18 → 236
      beta3GnTL1_like; Beta 1, 3-N-acetylglucosaminyltransferase is essential for the formation of poly-N-acetyllactosamine

    RNA

    1. XR_010055216.1 RNA Sequence

    2. XR_005489895.2 RNA Sequence

    3. XR_005489896.2 RNA Sequence

    4. XR_010055219.1 RNA Sequence

    5. XR_010055218.1 RNA Sequence

    6. XR_010055217.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6GV29.1 GenPept UniProtKB/Swiss-Prot:Q6GV29

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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