Chst5 carbohydrate sulfotransferase 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Chst5provided by RGD
Official Full Name: carbohydrate sulfotransferase 5provided by RGD
Primary source: RGD:1561144
See related: EnsemblRapid:ENSRNOG00000021521 AllianceGenome:RGD:1561144
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1561144
Summary: Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and keratan sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and keratan sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to several human genes including CHST6 (carbohydrate sulfotransferase 6). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Uterus (RPKM 9.4), Brain (RPKM 9.0) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 19q12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	19	NC_086037.1 (56769991..56790276, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	19	NC_051354.1 (39860729..39881019, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	19	NC_005118.4 (44115065..44136092, complement)

Chromosome 19 - NC_086037.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acetylglucosamine 6-O-sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acetylglucosamine 6-O-sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables keratan sulfotransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in N-acetylglucosamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in N-acetylglucosamine metabolic process	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in keratan sulfate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in keratan sulfate biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in sulfur compound metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: carbohydrate sulfotransferase 5

Names: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5

NP_001100901.1

EC 2.8.2.-

XP_006255694.1

EC 2.8.2.-

XP_006255695.1

EC 2.8.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.