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    Tesmin testis expressed metallothionein like protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 309142, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tesminprovided by RGD
    Official Full Name
    testis expressed metallothionein like proteinprovided by RGD
    Primary source
    RGD:1309788
    See related
    EnsemblRapid:ENSRNOG00000014671 AllianceGenome:RGD:1309788
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mtl5
    Summary
    Predicted to be involved in male meiotic nuclear division; regulation of DNA-templated transcription; and spermatogenesis. Predicted to be located in cytoplasm and male germ cell nucleus. Predicted to be active in nucleus. Orthologous to human TESMIN (testis expressed metallothionein like protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 147.0) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tesmin in Genome Data Viewer
    Location:
    1q42
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (210059414..210077704)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (200629688..200648434)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (218632764..218651054)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L21 Neighboring gene carnitine palmitoyltransferase 1A Neighboring gene uncharacterized LOC134483953 Neighboring gene galanin and GMAP prepropeptide Neighboring gene protein phosphatase 6, regulatory subunit 3 Neighboring gene RNA, U6 small nuclear 993

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in male meiotic nuclear division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in male germ cell nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tesmin
    Names
    metallothionein-like 5, testis-specific (tesmin)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012069.2NP_001012069.2  tesmin

      See identical proteins and their annotated locations for NP_001012069.2

      Status: VALIDATED

      Source sequence(s)
      BC083920, CB708158
      UniProtKB/Swiss-Prot
      Q5XHX9
      UniProtKB/TrEMBL
      A0A8I6G546
      Related
      ENSRNOP00000019861.4, ENSRNOT00000019861.8
      Conserved Domains (1) summary
      pfam03638
      Location:334371
      TCR; Tesmin/TSO1-like CXC domain, cysteine-rich domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      210059414..210077704
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079294.2XP_038935222.1  tesmin isoform X1

      UniProtKB/TrEMBL
      A6HYK6