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    Josd1 Josephin domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315134, updated on 27-Dec-2024

    Summary

    Official Symbol
    Josd1provided by RGD
    Official Full Name
    Josephin domain containing 1provided by RGD
    Primary source
    RGD:1305388
    See related
    EnsemblRapid:ENSRNOG00000014440 AllianceGenome:RGD:1305388
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305388
    Summary
    Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in protein deubiquitination and proteolysis. Predicted to be located in cytoplasm and plasma membrane. Orthologous to human JOSD1 (Josephin domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 129.2), Kidney (RPKM 114.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Josd1 in Genome Data Viewer
    Location:
    7q34
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (113110709..113124632, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (111230318..111244241, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120905343..120919261, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479938 Neighboring gene chibby 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22 Neighboring gene GTP binding protein 1 Neighboring gene Sad1 and UNC84 domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC109161

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    josephin-1
    Names
    josephin domain-containing protein 1
    NP_001020180.1
    XP_038935196.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025009.1NP_001020180.1  josephin-1

      See identical proteins and their annotated locations for NP_001020180.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091280
      UniProtKB/Swiss-Prot
      Q5BJY4
      UniProtKB/TrEMBL
      A6HST3
      Related
      ENSRNOP00000019612.4, ENSRNOT00000019612.8
      Conserved Domains (1) summary
      pfam02099
      Location:31173
      Josephin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      113110709..113124632 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079268.2XP_038935196.1  josephin-1 isoform X1

      Conserved Domains (1) summary
      pfam02099
      Location:31103
      Josephin