Abca15 ATP-binding cassette, subfamily A (ABC1), member 15 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Abca15provided by RGD
Official Full Name: ATP-binding cassette, subfamily A (ABC1), member 15provided by RGD
Primary source: RGD:1305981
See related: EnsemblRapid:ENSRNOG00000027505 AllianceGenome:RGD:1305981
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human ABCA15P (ATP binding cassette subfamily A member 15, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 19.8) and Kidney (RPKM 9.0) See more
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Genomic context

Location:: 1q36

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (184118017..184224881)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (174686666..174794395)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (190072348..190178870)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables lipid transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in hematopoietic progenitor cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in lipid transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in intracellular membrane-bounded organelle	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ATP-binding cassette, sub-family A (ABC1), member 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106293.2 → NP_001099763.2 ATP-binding cassette, sub-family A (ABC1), member 15

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

D4ACN5

Related

ENSRNOP00000033528.5, ENSRNOT00000037026.7

Conserved Domains (4) summary

TIGR01188
Location:1369 → 1662

drrA; daunorubicin resistance ABC transporter ATP-binding subunit

cd03263
Location:522 → 743

ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

COG1131
Location:522 → 834

CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]

pfam12698
Location:255 → 464

ABC2_membrane_3; ABC-2 family transporter protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

184118017..184224881

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017588989.3 → XP_017444478.1 ATP-binding cassette, sub-family A (ABC1), member 15 isoform X1
XM_039107026.2 → XP_038962954.1 ATP-binding cassette, sub-family A (ABC1), member 15 isoform X2

Conserved Domains (1) summary

TIGR01257
Location:8 → 1305

rim_protein; retinal-specific rim ABC transporter
XM_039107027.2 → XP_038962955.1 ATP-binding cassette, sub-family A (ABC1), member 15 isoform X3

Conserved Domains (1) summary

TIGR01257
Location:12 → 1054

rim_protein; retinal-specific rim ABC transporter