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    Nrsn1 neurensin 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291129, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nrsn1provided by RGD
    Official Full Name
    neurensin 1provided by RGD
    Primary source
    RGD:1307833
    See related
    EnsemblRapid:ENSRNOG00000017444 AllianceGenome:RGD:1307833
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Vmp
    Summary
    Predicted to be involved in nervous system development. Predicted to be located in cytoplasmic vesicle and growth cone. Predicted to be active in neuron projection; neuronal cell body; and transport vesicle. Orthologous to human NRSN1 (neurensin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 285.4) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Nrsn1 in Genome Data Viewer
    Location:
    17p11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (40234302..40252614)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (39806238..39824550)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (41798767..41816346)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene transfer RNA proline (anticodon AGG) 58 Neighboring gene triosephosphate isomerase 1, pseudogene 2 Neighboring gene uncharacterized LOC134482709 Neighboring gene doublecortin domain containing 2 Neighboring gene ribosomal protein L32, pseudogene 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Developmentally regulated expression of Neuro-p24 and its possible function in neurite extension. Araki M, et al. Neurosci Res, 2002 Dec. PMID 12445626
    2. A newly identified membrane protein localized exclusively in intracellular organelles of neurons. Kadota Y, et al. Brain Res Mol Brain Res, 1997 Jun. PMID 9191101
    3. Molecular characterization of a transport vesicle protein Neurensin-2, a homologue of Neurensin-1, expressed in neural cells. Nakanishi K, et al. Brain Res, 2006 Apr 7. PMID 16527258
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nervous system development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in growth cone ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    neurensin-1
    Names
    vesicular membrane protein p24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106109.2 → NP_001099579.2  neurensin-1

      See identical proteins and their annotated locations for NP_001099579.2

      Status: PROVISIONAL

      Source sequence(s)
      BC166919
      UniProtKB/TrEMBL
      B2RYS1
      Related
      ENSRNOP00000023519.3, ENSRNOT00000023519.7
      Conserved Domains (1) summary
      pfam14927
      Location:24 → 154
      Neurensin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      40234302..40252614
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039095508.2 → XP_038951436.1  neurensin-1 isoform X1

      UniProtKB/TrEMBL
      A6KLD9, G3V892
      Conserved Domains (1) summary
      pfam14927
      Location:24 → 154
      Neurensin
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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