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    Mybphl myosin binding protein H-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310782, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mybphlprovided by RGD
    Official Full Name
    myosin binding protein H-likeprovided by RGD
    Primary source
    RGD:1310511
    See related
    EnsemblRapid:ENSRNOG00000037082 AllianceGenome:RGD:1310511
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310511
    Summary
    Predicted to act upstream of or within in utero embryonic development. Predicted to be located in myofilament. Orthologous to human MYBPHL (myosin binding protein H like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 133.9), Lung (RPKM 27.7) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Mybphl in Genome Data Viewer
    Location:
    2q34
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (198692857..198706953)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (196005297..196018826)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (211158902..211173036)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit alpha 5 Neighboring gene sortilin 1 Neighboring gene uncharacterized LOC134485672 Neighboring gene proline and serine rich coiled-coil 1 Neighboring gene cadherin, EGF LAG seven-pass G-type receptor 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in myofilament  
    located_in myofilament  
    located_in sarcomere  

    General protein information

    Preferred Names
    myosin-binding protein H-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014042.1NP_001014064.1  myosin-binding protein H-like

      See identical proteins and their annotated locations for NP_001014064.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087113
      UniProtKB/Swiss-Prot
      Q5PQM4
      UniProtKB/TrEMBL
      A6HUZ7
      Related
      ENSRNOP00000027099.4, ENSRNOT00000027099.7
      Conserved Domains (5) summary
      cd00096
      Location:281345
      Ig; Immunoglobulin domain
      smart00410
      Location:62143
      IG_like; Immunoglobulin like
      cd00063
      Location:147235
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:262351
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:71143
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      198692857..198706953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233150.5XP_006233212.1  myosin-binding protein H-like isoform X1

      See identical proteins and their annotated locations for XP_006233212.1

      UniProtKB/Swiss-Prot
      Q5PQM4
      UniProtKB/TrEMBL
      A6HUZ7
      Conserved Domains (5) summary
      cd00096
      Location:281345
      Ig; Immunoglobulin domain
      smart00410
      Location:62143
      IG_like; Immunoglobulin like
      cd00063
      Location:147235
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:262351
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:71143
      Ig; Immunoglobulin domain
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