Slc25a24 solute carrier family 25 member 24 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc25a24provided by RGD
Official Full Name: solute carrier family 25 member 24provided by RGD
Primary source: RGD:1311982
See related: EnsemblRapid:ENSRNOG00000020470 AllianceGenome:RGD:1311982
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable ADP:phosphate antiporter activity; ATP:phosphate antiporter activity; and calcium ion binding activity. Predicted to be involved in cellular response to calcium ion; cellular response to oxidative stress; and purine ribonucleotide transport. Predicted to be located in membrane and mitochondrion. Orthologous to human SLC25A24 (solute carrier family 25 member 24). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Adrenal (RPKM 133.9), Lung (RPKM 96.7) and 9 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2q41

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (199449425..199487287)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (196761076..196799236)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (211930371..211967511)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ADP:phosphate antiporter activity	ISO Inferred from Sequence Orthology more info
enables ATP transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATP transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables ATP:phosphate antiporter activity	ISO Inferred from Sequence Orthology more info
enables adenine nucleotide transmembrane transporter activity	ISO Inferred from Sequence Orthology more info
enables calcium ion binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in ADP transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in ATP transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in adenine nucleotide transport	ISO Inferred from Sequence Orthology more info
involved_in cellular response to calcium ion	ISO Inferred from Sequence Orthology more info
involved_in cellular response to oxidative stress	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial ATP transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial transport	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: calcium-binding mitochondrial carrier protein SCaMC-1

Names: solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127544.1 → NP_001121016.1 calcium-binding mitochondrial carrier protein SCaMC-1

See identical proteins and their annotated locations for NP_001121016.1

Status: PROVISIONAL

Source sequence(s)

CH473952

UniProtKB/TrEMBL

B1WC67, F7EXY7

Related

ENSRNOP00000027765.6, ENSRNOT00000027765.7

Conserved Domains (2) summary

COG5126
Location:28 → 155

FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]

PTZ00169
Location:199 → 470

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional