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    Prr3 proline rich 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361788, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prr3provided by RGD
    Official Full Name
    proline rich 3provided by RGD
    Primary source
    RGD:1303270
    See related
    AllianceGenome:RGD:1303270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cat56
    Summary
    Predicted to enable metal ion binding activity. Orthologous to human PRR3 (proline rich 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 85.8), Brain (RPKM 80.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Prr3 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2797677..2804674)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2792868..2799865)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3300247..3307262)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene RT1 class I, locus T24, gene 1 Neighboring gene uncharacterized LOC134483845 Neighboring gene G protein nucleolar 1 Neighboring gene ATP binding cassette subfamily F member 1 Neighboring gene microRNA 877 Neighboring gene protein phosphatase 1, regulatory subunit 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, et al. Genome Res, 2004 Apr. PMID 15060004, Free PMC Article
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC156547

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 3
    Names
    MHC class I region proline-rich protein CAT56
    proline-rich polypeptide 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212544.2 → NP_997709.1  proline-rich protein 3

      See identical proteins and their annotated locations for NP_997709.1

      Status: VALIDATED

      Source sequence(s)
      BC126073
      UniProtKB/Swiss-Prot
      A0JN06, Q6MG07
      UniProtKB/TrEMBL
      A0A0G2K9X6, A6KT60
      Conserved Domains (1) summary
      pfam00642
      Location:155 → 179
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      2797677..2804674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006255943.4 → XP_006256005.1  proline-rich protein 3 isoform X2

      Conserved Domains (1) summary
      pfam00642
      Location:98 → 122
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

    2. XM_063279199.1 → XP_063135269.1  proline-rich protein 3 isoform X4

      UniProtKB/TrEMBL
      A0A8I5ZX98

    3. XM_063279198.1 → XP_063135268.1  proline-rich protein 3 isoform X3

    4. XM_039098790.2 → XP_038954718.1  proline-rich protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A8L2QGF9, A6KT61
      Conserved Domains (1) summary
      pfam00642
      Location:112 → 136
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6MG07.1 GenPept UniProtKB/Swiss-Prot:Q6MG07

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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