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    Ptgfr prostaglandin F receptor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25652, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptgfrprovided by RGD
    Official Full Name
    prostaglandin F receptorprovided by RGD
    Primary source
    RGD:3436
    See related
    EnsemblRapid:ENSRNOG00000046468 AllianceGenome:RGD:3436
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PF2AR
    Summary
    Predicted to enable prostaglandin F receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin D stimulus; and response to estradiol. Predicted to act upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in plasma membrane. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 285.1), Liver (RPKM 73.0) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Ptgfr in Genome Data Viewer
    Location:
    2q45
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (243390820..243426647, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (240731185..240766674, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (257005813..257039036, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene interferon-induced protein 44 Neighboring gene interferon-induced protein 44-like Neighboring gene proteasome maturation protein pseudogene Neighboring gene protein tyrosine phosphatase 4A1 like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables prostaglandin F receptor activity  
    enables prostaglandin F receptor activity  
    Component Evidence Code Pubs
    located_in cytoplasm  
    located_in extracellular region  
    is_active_in plasma membrane  
    located_in plasma membrane  

    General protein information

    Preferred Names
    prostaglandin F2-alpha receptor
    Names
    PGF receptor
    PGF2-alpha receptor
    prostanoid FP receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013115.2NP_037247.1  prostaglandin F2-alpha receptor

      See identical proteins and their annotated locations for NP_037247.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      P43118, Q62787
      UniProtKB/TrEMBL
      A6HWJ3
      Related
      ENSRNOP00000065253.1, ENSRNOT00000071195.3
      Conserved Domains (1) summary
      cd15145
      Location:27316
      7tmA_FP; prostaglandin F2-alpha receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      243390820..243426647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233486.5XP_006233548.1  prostaglandin F2-alpha receptor isoform X1

      See identical proteins and their annotated locations for XP_006233548.1

      UniProtKB/Swiss-Prot
      P43118, Q62787
      UniProtKB/TrEMBL
      A6HWJ3
      Conserved Domains (1) summary
      cd15145
      Location:27316
      7tmA_FP; prostaglandin F2-alpha receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. XM_006233487.5XP_006233549.1  prostaglandin F2-alpha receptor isoform X1

      See identical proteins and their annotated locations for XP_006233549.1

      UniProtKB/Swiss-Prot
      P43118, Q62787
      UniProtKB/TrEMBL
      A6HWJ3
      Conserved Domains (1) summary
      cd15145
      Location:27316
      7tmA_FP; prostaglandin F2-alpha receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
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