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    Allc allantoicase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 246758, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Allcprovided by RGD
    Official Full Name
    allantoicaseprovided by RGD
    Primary source
    RGD:621804
    See related
    EnsemblRapid:ENSRNOG00000008299 AllianceGenome:RGD:621804
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable allantoicase activity. Predicted to be involved in allantoin catabolic process. Orthologous to human ALLC (allantoicase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 376.6) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Allc in Genome Data Viewer
    Location:
    6q16
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (50907575..50942665, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (45179181..45214275, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (47812989..47848068, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene aldo-keto reductase family 1, member B1 (aldose reductase), pseudogene 1 Neighboring gene doublecortin domain containing 2C Neighboring gene U6 spliceosomal RNA Neighboring gene collectin sub-family member 11 Neighboring gene ribosomal protein S7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Selective pressure on the allantoicase gene during vertebrate evolution. Vigetti D, et al. J Mol Evol, 2003 Dec. PMID 14745534
    2. Genomic organization and chromosome localization of the murine and human allantoicase gene. Vigetti D, et al. Gene, 2002 May 1. PMID 12036579
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables allantoicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in allantoin catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    probable inactive allantoicase
    Names
    allantoate amidinohydrolase
    probable allantoicase
    NP_001013055.1
    XP_006240006.1
    XP_038967716.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013037.1 → NP_001013055.1  probable inactive allantoicase

      See identical proteins and their annotated locations for NP_001013055.1

      Status: PROVISIONAL

      Source sequence(s)
      BC078971
      UniProtKB/Swiss-Prot
      Q6AYP0, Q8K470
      UniProtKB/TrEMBL
      A6HB08
      Related
      ENSRNOP00000011048.6, ENSRNOT00000011048.8
      Conserved Domains (2) summary
      TIGR02961
      Location:18 → 385
      allantoicase; allantoicase
      pfam03561
      Location:28 → 200
      Allantoicase; Allantoicase repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      50907575..50942665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006239944.5 → XP_006240006.1  probable inactive allantoicase isoform X1

      See identical proteins and their annotated locations for XP_006240006.1

      UniProtKB/Swiss-Prot
      Q6AYP0, Q8K470
      UniProtKB/TrEMBL
      A6HB08
      Conserved Domains (2) summary
      TIGR02961
      Location:18 → 385
      allantoicase; allantoicase
      pfam03561
      Location:28 → 200
      Allantoicase; Allantoicase repeat

    2. XM_039111788.2 → XP_038967716.1  probable inactive allantoicase isoform X2

      Conserved Domains (1) summary
      cl27253
      Location:38 → 277
      Alc; Allantoicase [Nucleotide transport and metabolism]
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AYP0.1 GenPept UniProtKB/Swiss-Prot:Q6AYP0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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