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    Hoxb2 homeobox B2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361765, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hoxb2provided by RGD
    Official Full Name
    homeobox B2provided by RGD
    Primary source
    RGD:2319509
    See related
    EnsemblRapid:ENSRNOG00000008365 AllianceGenome:RGD:2319509
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Hoxbes2
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including central nervous system development; embryonic skeletal system morphogenesis; and regionalization. Predicted to be located in nucleoplasm. Orthologous to human HOXB2 (homeobox B2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 67.1), Adrenal (RPKM 49.1) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Hoxb2 in Genome Data Viewer
    Location:
    10q26
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (81814340..81816731)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (81317828..81320220)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (84200859..84203065)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene homeo box B4 Neighboring gene homeo box B3 Neighboring gene uncharacterized LOC102550580 Neighboring gene homeo box B1 Neighboring gene uncharacterized LOC120095284 Neighboring gene uncharacterized LOC120095285

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in nucleoplasm  
    located_in nucleoplasm  
    is_active_in nucleus  

    General protein information

    Preferred Names
    homeobox protein Hox-B2
    Names
    Hoxb2-like epididymal protein
    homeo box B2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399735.1 → NP_001386664.1  homeobox protein Hox-B2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A6HIF1, D4A426
      Related
      ENSRNOP00000011213.5, ENSRNOT00000011213.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      81814340..81816731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

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