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    Pus7l pseudouridine synthase 7 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315264, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pus7lprovided by RGD
    Official Full Name
    pseudouridine synthase 7 likeprovided by RGD
    Primary source
    RGD:1304692
    See related
    EnsemblRapid:ENSRNOG00000022570 AllianceGenome:RGD:1304692
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304692
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to be involved in mRNA pseudouridine synthesis. Predicted to be active in nucleus. Orthologous to human PUS7L (pseudouridine synthase 7 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 21.2), Adrenal (RPKM 20.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Pus7l in Genome Data Viewer
    Location:
    7q35
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (127538785..127561936, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (125659507..125706582, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (135765307..135803818, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 20 Neighboring gene uncharacterized LOC134479779 Neighboring gene uncharacterized LOC108351538 Neighboring gene uncharacterized LOC108351537 Neighboring gene ribosomal protein L18, pseudogene 11 Neighboring gene interleukin-1 receptor-associated kinase 4 Neighboring gene twinfilin actin-binding protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pseudouridine synthase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA pseudouridine synthesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    pseudouridine synthase 7 like; pseudouridylate synthase PUS7L
    Names
    pseudouridylate synthase 7 homolog-like
    pseudouridylate synthase 7-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001432479.1 → NP_001419408.1  pseudouridine synthase 7 like

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      D4ABN2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      127538785..127561936 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017595307.3 → XP_017450796.1  pseudouridylate synthase PUS7L

      UniProtKB/TrEMBL
      D4ABN2
      Conserved Domains (2) summary
      cd02576
      Location:311 → 705
      PseudoU_synth_ScPUS7; Pseudouridine synthase, TruD family
      cl00130
      Location:22 → 46
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

    2. XM_039080339.1 → XP_038936267.1  pseudouridylate synthase PUS7L

      UniProtKB/TrEMBL
      D4ABN2
      Conserved Domains (2) summary
      cd02576
      Location:311 → 705
      PseudoU_synth_ScPUS7; Pseudouridine synthase, TruD family
      cl00130
      Location:22 → 46
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

    3. XM_002729847.6 → XP_002729893.2  pseudouridylate synthase PUS7L

      Related
      ENSRNOP00000101457.1, ENSRNOT00000159786.1
      Conserved Domains (2) summary
      cd02576
      Location:311 → 705
      PseudoU_synth_ScPUS7; Pseudouridine synthase, TruD family
      cl00130
      Location:22 → 46
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

    4. XM_006242271.5 → XP_006242333.2  pseudouridylate synthase PUS7L

      UniProtKB/TrEMBL
      D4ABN2
      Related
      ENSRNOP00000108220.1, ENSRNOT00000133395.1
      Conserved Domains (2) summary
      cd02576
      Location:311 → 705
      PseudoU_synth_ScPUS7; Pseudouridine synthase, TruD family
      cl00130
      Location:22 → 46
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

    5. XM_063264454.1 → XP_063120524.1  pseudouridylate synthase PUS7L

      UniProtKB/TrEMBL
      D4ABN2
      Related
      ENSRNOP00000033040.6, ENSRNOT00000029097.8
    Nucleotide Protein Strain
    Heading Accession and Version

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