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    Syt16 synaptotagmin 16 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299142, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Syt16provided by RGD
    Official Full Name
    synaptotagmin 16provided by RGD
    Primary source
    RGD:1564654
    See related
    EnsemblRapid:ENSRNOG00000056012 AllianceGenome:RGD:1564654
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564654
    Summary
    Predicted to enable identical protein binding activity and phospholipid binding activity. Orthologous to human SYT16 (synaptotagmin 16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 37.8), Adrenal (RPKM 5.4) and 5 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Syt16 in Genome Data Viewer
    Location:
    6q24
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (98456582..98735306)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (92721415..92972140)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (97076304..97199856)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103553 Neighboring gene transmembrane protein 183A, pseudogene 2 Neighboring gene uncharacterized LOC134479220 Neighboring gene hypoxia inducible factor 1 subunit alpha Neighboring gene small nuclear RNA activating complex, polypeptide 1 Neighboring gene uncharacterized LOC102550910 Neighboring gene potassium voltage-gated channel subfamily H member 5 Neighboring gene ras homolog family member J

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans. Fukuda M. J Biochem, 2003 May. PMID 12801916
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables calcium-dependent phospholipid binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipid binding ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    synaptotagmin 16; synaptotagmin-16
    Names
    synaptotagmin XVI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001428632.1 → NP_001415561.1  synaptotagmin 16 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A0G2K644

    2. NM_001428633.1 → NP_001415562.1  synaptotagmin 16 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A0G2K644

    3. NM_001428634.1 → NP_001415563.1  synaptotagmin 16 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A0G2K644

    4. NM_001428635.1 → NP_001415564.1  synaptotagmin 16 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    5. NM_001428636.1 → NP_001415565.1  synaptotagmin 16 isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      98456582..98735306
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063262672.1 → XP_063118742.1  synaptotagmin-16 isoform X3

    2. XM_039113257.2 → XP_038969185.1  synaptotagmin-16 isoform X2

      Related
      ENSRNOP00000086006.2, ENSRNOT00000113442.2
      Conserved Domains (2) summary
      cd08389
      Location:239 → 362
      C2A_Synaptotagmin-14_16; C2A domain first repeat present in Synaptotagmins 14 and 16
      cd08408
      Location:395 → 532
      C2B_Synaptotagmin-14_16; C2 domain second repeat present in Synaptotagmins 14 and 16

    3. XM_063262673.1 → XP_063118743.1  synaptotagmin-16 isoform X3

    4. XM_063262671.1 → XP_063118741.1  synaptotagmin-16 isoform X1

    5. XM_234300.9 → XP_234300.4  synaptotagmin-16 isoform X1

      See identical proteins and their annotated locations for XP_234300.4

      UniProtKB/TrEMBL
      A0A0G2K644
      Related
      ENSRNOP00000073667.1, ENSRNOT00000088430.3
      Conserved Domains (2) summary
      cd08389
      Location:349 → 472
      C2A_Synaptotagmin-14_16; C2A domain first repeat present in Synaptotagmins 14 and 16
      cd08408
      Location:505 → 642
      C2B_Synaptotagmin-14_16; C2 domain second repeat present in Synaptotagmins 14 and 16

    6. XM_063262674.1 → XP_063118744.1  synaptotagmin-16 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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