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    Rtf1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [ Rattus norvegicus (Norway rat) ]

    Gene ID: 366169, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rtf1provided by RGD
    Official Full Name
    Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)provided by RGD
    Primary source
    RGD:1310654
    See related
    EnsemblRapid:ENSRNOG00000005183 AllianceGenome:RGD:1310654
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gtl7
    Summary
    Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity and single-stranded DNA binding activity. Predicted to be involved in several processes, including endodermal cell fate commitment; negative regulation of transcription by RNA polymerase II; and transcription elongation by RNA polymerase II. Predicted to act upstream of or within blastocyst growth. Predicted to be located in nucleolus. Predicted to be part of Cdc73/Paf1 complex. Orthologous to human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 54.2), Adrenal (RPKM 53.1) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rtf1 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (127113171..127172761)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (106659363..106718956)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (111478350..111537941)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene Opa interacting protein 5 Neighboring gene nucleolar and spindle associated protein 1 Neighboring gene 40S ribosomal protein S20 pseudogene Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 1 Neighboring gene inositol-trisphosphate 3-kinase A Neighboring gene leukocyte receptor tyrosine kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex  
    part_of Cdc73/Paf1 complex  
    located_in nucleolus  

    General protein information

    Preferred Names
    RNA polymerase-associated protein RTF1 homolog
    Names
    gene trap locus 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401979.1NP_001388908.1  RNA polymerase-associated protein RTF1 homolog precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A8I6AGX2
      Related
      ENSRNOP00000094041.1, ENSRNOT00000105159.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      127113171..127172761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063284277.1XP_063140347.1  RNA polymerase-associated protein RTF1 homolog isoform X1

      Related
      ENSRNOP00000053231.3, ENSRNOT00000056392.4

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