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    Rhog ras homolog family member G [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308875, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rhogprovided by RGD
    Official Full Name
    ras homolog family member Gprovided by RGD
    Primary source
    RGD:621310
    See related
    EnsemblRapid:ENSRNOG00000020393 AllianceGenome:RGD:621310
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Arhg
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; activation of GTPase activity; and cytoskeleton organization. Predicted to act upstream of or within several processes, including Rho protein signal transduction; positive regulation of DNA-templated transcription; and regulation of ruffle assembly. Predicted to be active in several cellular components, including cytoplasmic vesicle; glutamatergic synapse; and postsynapse. Orthologous to human RHOG (ras homolog family member G). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 120.2), Thymus (RPKM 108.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rhog in Genome Data Viewer
    Location:
    1q32
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (166030685..166046254, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (156618713..156630710, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (167336147..167347720, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene nucleoporin 98 and 96 precursor Neighboring gene glutathione peroxidase 4, pseudogene 1 Neighboring gene post-GPI attachment to proteins 2 Neighboring gene ribosomal protein S29, pseudogene 1 Neighboring gene stromal interaction molecule 1 Neighboring gene ribosome biogenesis protein NSA2 homolog pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Clone Names

    • MGC125105

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTPase activity  
    enables GTPase activity  
    enables protein kinase binding  
    Process Evidence Code Pubs
    involved_in Rac protein signal transduction  
    acts_upstream_of_or_within Rac protein signal transduction  
    acts_upstream_of_or_within Rho protein signal transduction  
    acts_upstream_of_or_within actin cytoskeleton organization  
    involved_in actin filament organization  
    involved_in activation of GTPase activity  
    involved_in cell chemotaxis  
    involved_in cell chemotaxis  
    involved_in cortical cytoskeleton organization  
    involved_in establishment or maintenance of cell polarity  
    acts_upstream_of_or_within positive regulation of DNA-templated transcription  
    involved_in positive regulation of protein localization to plasma membrane  
    involved_in regulation of actin cytoskeleton organization  
    involved_in regulation of cell shape  
    involved_in regulation of postsynapse assembly  
    acts_upstream_of_or_within regulation of ruffle assembly  
    Component Evidence Code Pubs
    is_active_in cell projection  
    is_active_in cytoplasmic vesicle  
    is_active_in cytoskeleton  
    is_active_in glutamatergic synapse  
    is_active_in plasma membrane  
    is_active_in postsynapse  

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoG
    Names
    ras homolog gene family, member G (rho G)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037195.1NP_001032272.1  rho-related GTP-binding protein RhoG

      See identical proteins and their annotated locations for NP_001032272.1

      Status: PROVISIONAL

      Source sequence(s)
      BC107943
      UniProtKB/TrEMBL
      A0A8I6A3A8, Q32PX6
      Related
      ENSRNOP00000106348.1, ENSRNOT00000138188.1
      Conserved Domains (1) summary
      cd01875
      Location:1191
      RhoG; Ras homolog family, member G (RhoG) of small guanosine triphosphatases (GTPases)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      166030685..166046254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006229882.5XP_006229944.1  rho-related GTP-binding protein RhoG isoform X1

      See identical proteins and their annotated locations for XP_006229944.1

      UniProtKB/TrEMBL
      A0A8I6A3A8, Q32PX6
      Related
      ENSRNOP00000103714.1, ENSRNOT00000169387.1
      Conserved Domains (1) summary
      cd01875
      Location:1191
      RhoG; Ras homolog family, member G (RhoG) of small guanosine triphosphatases (GTPases)
    2. XM_006229883.5XP_006229945.1  rho-related GTP-binding protein RhoG isoform X1

      See identical proteins and their annotated locations for XP_006229945.1

      UniProtKB/TrEMBL
      A0A8I6A3A8, Q32PX6
      Conserved Domains (1) summary
      cd01875
      Location:1191
      RhoG; Ras homolog family, member G (RhoG) of small guanosine triphosphatases (GTPases)
    3. XM_063262837.1XP_063118907.1  rho-related GTP-binding protein RhoG isoform X1

      UniProtKB/TrEMBL
      A0A8I6A3A8, Q32PX6
      Related
      ENSRNOP00000099944.1, ENSRNOT00000142772.1
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