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    Eif3k eukaryotic translation initiation factor 3, subunit K [ Rattus norvegicus (Norway rat) ]

    Gene ID: 292762, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eif3kprovided by RGD
    Official Full Name
    eukaryotic translation initiation factor 3, subunit Kprovided by RGD
    Primary source
    RGD:1309221
    See related
    EnsemblRapid:ENSRNOG00000020495 AllianceGenome:RGD:1309221
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Eif3s12; PLAC-24
    Summary
    Predicted to enable RNA binding activity and ribosome binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytosol. Predicted to be part of eukaryotic translation initiation factor 3 complex. Orthologous to human EIF3K (eukaryotic translation initiation factor 3 subunit K). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 516.6), Thymus (RPKM 505.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eif3k in Genome Data Viewer
    Location:
    1q21
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (93387628..93397551, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (84260127..84270051, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (87927142..87937033, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene MARCKS-related protein-like Neighboring gene uncharacterized LOC102550499 Neighboring gene calpain 12 Neighboring gene actinin alpha 4 Neighboring gene mitogen activated protein kinase kinase kinase kinase 1 Neighboring gene ryanodine receptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding  
    enables ribosome binding  
    contributes_to translation initiation factor activity  
    contributes_to translation initiation factor activity  
    Component Evidence Code Pubs
    located_in cytosol  
    located_in cytosol  
    part_of eukaryotic 43S preinitiation complex  
    part_of eukaryotic 48S preinitiation complex  
    part_of eukaryotic translation initiation factor 3 complex  
    part_of eukaryotic translation initiation factor 3 complex  
    located_in nucleus  

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 3 subunit K
    Names
    eukaryotic translation initiation factor 3, subunit 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398703.1NP_001385632.1  eukaryotic translation initiation factor 3 subunit K

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A0A8I5ZX76, A0A8I6AFY5, A6J9M3
      Related
      ENSRNOP00000083732.1, ENSRNOT00000118913.2
      Conserved Domains (1) summary
      pfam10075
      Location:61189
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      93387628..93397551 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283417.1XP_063139487.1  eukaryotic translation initiation factor 3 subunit K isoform X1

      UniProtKB/TrEMBL
      A0A8I6AIB7
      Related
      ENSRNOP00000094716.1, ENSRNOT00000112033.2
    2. XM_039104247.2XP_038960175.1  eukaryotic translation initiation factor 3 subunit K isoform X2

      Conserved Domains (1) summary
      cl24019
      Location:61118
      CSN8_PSD8_EIF3K; CSN8/PSMD8/EIF3K family

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