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    Rps4x ribosomal protein S4, X-linked [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100362640, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rps4xprovided by RGD
    Official Full Name
    ribosomal protein S4, X-linkedprovided by RGD
    Primary source
    RGD:2324318
    See related
    EnsemblRapid:ENSRNOG00000003201 AllianceGenome:RGD:2324318
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in response to ethanol. Located in ribosome. Orthologous to human RPS4X (ribosomal protein S4 X-linked). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 6914.9), Thymus (RPKM 6642.1) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rps4x in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (71338478..71342921, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (67298522..67302965, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (72074108..72078551, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene ERCC excision repair 6 like, spindle assembly checkpoint helicase Neighboring gene uncharacterized LOC134484080 Neighboring gene small nuclear ribonucleoprotein D2 polypeptide, pseudogene 2 Neighboring gene uncharacterized LOC120099193 Neighboring gene Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC105788

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to ethanol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein eS4
    Names
    ribosomal protein S4, X-linked X-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007600.2NP_001007601.1  small ribosomal subunit protein eS4

      See identical proteins and their annotated locations for NP_001007601.1

      Status: VALIDATED

      Source sequence(s)
      BC086560, FN800320, JAXUCZ010000021
      UniProtKB/Swiss-Prot
      P62703
      UniProtKB/TrEMBL
      A0A8L2QYQ1, A6IQE4
      Related
      ENSRNOP00000067969.3, ENSRNOT00000076978.5
      Conserved Domains (1) summary
      PLN00036
      Location:1260
      PLN00036; 40S ribosomal protein S4; Provisional

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      71338478..71342921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)