Btf3 basic transcription factor 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Btf3provided by RGD
Official Full Name: basic transcription factor 3provided by RGD
Primary source: RGD:1308095
See related: EnsemblRapid:ENSRNOG00000016912 AllianceGenome:RGD:1308095
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of protein localization to endoplasmic reticulum. Predicted to act upstream of or within in utero embryonic development. Predicted to be located in cytoplasm. Predicted to be part of nascent polypeptide-associated complex. Predicted to be active in cytosol. Orthologous to human BTF3 (basic transcription factor 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 650.1), Spleen (RPKM 590.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q12

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (31394010..31401138, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (29659764..29666898, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (28417316..28424436, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Btf3 (e-PCR), detects polymorphism
- UniSTS:547194

MARC_7241-7242:996687679:1 (e-PCR)
- UniSTS:269746

MARC_7241-7242:1007583003:3 (e-PCR)
- UniSTS:269746

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
acts_upstream_of_or_within in utero embryonic development	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of protein localization to endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
part_of nascent polypeptide-associated complex	IBA Inferred from Biological aspect of Ancestor more info
part_of nascent polypeptide-associated complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: transcription factor BTF3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.