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    Mospd3 motile sperm domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288557, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Mospd3provided by RGD
    Official Full Name
    motile sperm domain containing 3provided by RGD
    Primary source
    RGD:1304973
    See related
    EnsemblRapid:ENSRNOG00000001396 AllianceGenome:RGD:1304973
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to act upstream of or within heart development. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human MOSPD3 (motile sperm domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 81.4), Thymus (RPKM 78.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Mospd3 in Genome Data Viewer
    Location:
    12q12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (24728012..24737078)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (19095203..19100303)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (22164978..22169251)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene F-box protein 24 Neighboring gene procollagen C-endopeptidase enhancer Neighboring gene transferrin receptor 2 Neighboring gene actin-like 6B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1. Yamaguchi T, et al. Brain Res, 2004 Oct 29. PMID 15464766
    2. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Pall GS, et al. Genomics, 2004 Dec. PMID 15533722
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC116409

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within heart development ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    motile sperm domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025629.1 → NP_001020800.1  motile sperm domain-containing protein 3

      See identical proteins and their annotated locations for NP_001020800.1

      Status: PROVISIONAL

      Source sequence(s)
      BC099230
      UniProtKB/TrEMBL
      A6J017, F7F0P6, Q4KLG1
      Conserved Domains (1) summary
      pfam00635
      Location:41 → 133
      Motile_Sperm; MSP (Major sperm protein) domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      24728012..24737078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039089204.2 → XP_038945132.1  motile sperm domain-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      A6J014
      Conserved Domains (1) summary
      pfam00635
      Location:41 → 133
      Motile_Sperm; MSP (Major sperm protein) domain

    2. XM_006249115.5 → XP_006249177.1  motile sperm domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006249177.1

      UniProtKB/TrEMBL
      A6J017, F7F0P6, Q4KLG1
      Related
      ENSRNOP00000001890.4, ENSRNOT00000001890.9
      Conserved Domains (1) summary
      pfam00635
      Location:41 → 133
      Motile_Sperm; MSP (Major sperm protein) domain
    Nucleotide Protein Strain
    Heading Accession and Version

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