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    Elp6 elongator acetyltransferase complex subunit 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363150, updated on 9-Dec-2024

    Summary

    Official Symbol
    Elp6provided by RGD
    Official Full Name
    elongator acetyltransferase complex subunit 6provided by RGD
    Primary source
    RGD:1305478
    See related
    EnsemblRapid:ENSRNOG00000020847 AllianceGenome:RGD:1305478
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tmem103; RGD1305478
    Summary
    Predicted to be involved in positive regulation of cell migration. Predicted to be located in cytosol and nucleus. Predicted to be part of elongator holoenzyme complex. Orthologous to human ELP6 (elongator acetyltransferase complex subunit 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 80.2), Kidney (RPKM 66.7) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Elp6 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (119158380..119173483)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (110280059..110295070)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (118525770..118541074)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene chondroitin sulfate proteoglycan 5 Neighboring gene ribosomal protein S23, pseudogene 11 Neighboring gene SREBF chaperone Neighboring gene protein tyrosine phosphatase, non-receptor type 23

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acts_upstream_of_or_within apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within cellular response to stress ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within homeostasis of number of retina cells ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within inflammasome-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within locomotory behavior ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within motor behavior ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within neuromuscular process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within neuromuscular process controlling balance ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within photoreceptor cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell migration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within protein folding ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to unfolded protein ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within retina development in camera-type eye ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA wobble uridine modification IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ubiquitin recycling ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of elongator holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of elongator holoenzyme complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of elongator holoenzyme complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of elongator holoenzyme complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    elongator complex protein 6
    Names
    UPF0405 protein C3orf75 homolog
    elongator complex protein 6 homolog
    transmembrane protein 103

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108782.2NP_001102252.1  elongator complex protein 6

      See identical proteins and their annotated locations for NP_001102252.1

      Status: PROVISIONAL

      Source sequence(s)
      BC166773
      UniProtKB/Swiss-Prot
      B2RYG8
      UniProtKB/TrEMBL
      A0A8I6AHA4
      Related
      ENSRNOP00000028288.5, ENSRNOT00000028288.9
      Conserved Domains (1) summary
      pfam09807
      Location:2251
      ELP6; Elongation complex protein 6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      119158380..119173483
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265837.1XP_063121907.1  elongator complex protein 6 isoform X1