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    Aknad1 AKNA domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691416, updated on 9-Dec-2024

    Summary

    Official Symbol
    Aknad1provided by RGD
    Official Full Name
    AKNA domain containing 1provided by RGD
    Primary source
    RGD:1583957
    See related
    EnsemblRapid:ENSRNOG00000028025 AllianceGenome:RGD:1583957
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human AKNAD1 (AKNA domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 21.6), Testes (RPKM 14.9) and 2 other tissues See more
    Orthologs
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    Genomic context

    See Aknad1 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (199076864..199120402)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (196385149..196432319)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (211541800..211585332)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene chloride channel CLIC-like 1 Neighboring gene G-protein signaling modulator 2 Neighboring gene uncharacterized LOC102547393 Neighboring gene syntaxin binding protein 3 Neighboring gene uncharacterized LOC134485674 Neighboring gene fibronectin type III domain containing 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044303.2NP_001037768.2  protein AKNAD1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein-coding transcript.
      Source sequence(s)
      BC079051, JAXUCZ010000002
      UniProtKB/TrEMBL
      F7FFB7
      Related
      ENSRNOP00000029704.6, ENSRNOT00000033443.7
      Conserved Domains (1) summary
      pfam12443
      Location:324416
      AKNA; AT-hook-containing transcription factor

    RNA

    1. NR_073134.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate acceptor splice site at an internal exon and lacks several exons at the 3' end compared to variant 1. It is represented as non-coding because a significant portion of the longest open reading frame (ORF) is in a different frame compared to variant 1, and there is no support for the predicted protein encoded by this ORF.
      Source sequence(s)
      BC079051

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      199076864..199120402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282594.1XP_063138664.1  protein AKNAD1 isoform X1

      UniProtKB/TrEMBL
      F7FFB7
    2. XM_063282593.1XP_063138663.1  protein AKNAD1 isoform X1

      UniProtKB/TrEMBL
      F7FFB7
    3. XM_039103167.2XP_038959095.1  protein AKNAD1 isoform X2

      UniProtKB/TrEMBL
      A6HV28
      Conserved Domains (1) summary
      pfam12443
      Location:340432
      AKNA; AT-hook-containing transcription factor
    4. XM_063282595.1XP_063138665.1  protein AKNAD1 isoform X1

      UniProtKB/TrEMBL
      F7FFB7

    RNA

    1. XR_005500370.2 RNA Sequence