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    Sec14l5 SEC14-like lipid binding 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287060, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Sec14l5provided by RGD
    Official Full Name
    SEC14-like lipid binding 5provided by RGD
    Primary source
    RGD:1564638
    See related
    EnsemblRapid:ENSRNOG00000002917 AllianceGenome:RGD:1564638
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564638
    Summary
    Predicted to be active in cytoplasm. Orthologous to human SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 108.4), Brain (RPKM 22.1) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Sec14l5 in Genome Data Viewer
    Location:
    10q12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (10901430..10942548, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (10394963..10436076, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (10588955..10629942, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 16 open reading frame 89 Neighboring gene ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Neighboring gene periplakin Neighboring gene ubinuclein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SEC14-like protein 5
    Names
    SEC14-like 5 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135710.2 → NP_001129182.2  SEC14-like protein 5

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6AE07, D4A8B0
      Related
      ENSRNOP00000057965.2, ENSRNOT00000061253.4
      Conserved Domains (4) summary
      smart01100
      Location:243 → 288
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:314 → 477
      CRAL_TRIO; CRAL/TRIO domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family
      cl18951
      Location:179 → 309
      Amidase; Amidase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      10901430..10942548 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006245783.5 → XP_006245845.1  SEC14-like protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE07, D4A8B0
      Conserved Domains (4) summary
      smart01100
      Location:243 → 288
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam00650
      Location:314 → 477
      CRAL_TRIO; CRAL/TRIO domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family
      cl18951
      Location:179 → 309
      Amidase; Amidase

    2. XM_039085333.2 → XP_038941261.1  SEC14-like protein 5 isoform X2

      Conserved Domains (1) summary
      smart00516
      Location:23 → 196
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    Nucleotide Protein Strain
    Heading Accession and Version

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