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    Zfp641 zinc finger protein 641 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300197, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp641provided by RGD
    Official Full Name
    zinc finger protein 641provided by RGD
    Primary source
    RGD:1310412
    See related
    EnsemblRapid:ENSRNOG00000032447 AllianceGenome:RGD:1310412
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Znf641; RGD1310412
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleolus. Predicted to be active in nucleoplasm. Orthologous to human ZNF641 (zinc finger protein 641). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 59.1), Adrenal (RPKM 44.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zfp641 in Genome Data Viewer
    Location:
    7q36
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (131313620..131324149, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (129434576..129444847, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (139897574..139907624, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1, pseudogene 4 Neighboring gene H1.7 linker histone Neighboring gene olfactory receptor family 8 subfamily S member 16 Neighboring gene olfactory receptor family 8 subfamily S member 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 641

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106792.2 → NP_001100262.1  zinc finger protein 641

      See identical proteins and their annotated locations for NP_001100262.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6KC69, D4A704
      Related
      ENSRNOP00000047139.3, ENSRNOT00000045473.7
      Conserved Domains (4) summary
      PLN03206
      Location:13 → 90
      PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
      smart00349
      Location:95 → 156
      KRAB; krueppel associated box
      COG5048
      Location:208 → 402
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:252 → 272
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      131313620..131324149 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039078916.2 → XP_038934844.1  zinc finger protein 641 isoform X2

      Conserved Domains (4) summary
      PLN03206
      Location:13 → 118
      PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
      smart00349
      Location:91 → 142
      KRAB; krueppel associated box
      COG5048
      Location:194 → 388
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:238 → 258
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039078915.2 → XP_038934843.1  zinc finger protein 641 isoform X1

      UniProtKB/TrEMBL
      A6KC69, D4A704
      Conserved Domains (4) summary
      PLN03206
      Location:13 → 90
      PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
      smart00349
      Location:95 → 156
      KRAB; krueppel associated box
      COG5048
      Location:208 → 402
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:252 → 272
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_039078914.2 → XP_038934842.1  zinc finger protein 641 isoform X1

      UniProtKB/TrEMBL
      A6KC69, D4A704
      Conserved Domains (4) summary
      PLN03206
      Location:13 → 90
      PLN03206; phosphoribosylformylglycinamidine synthase; Provisional
      smart00349
      Location:95 → 156
      KRAB; krueppel associated box
      COG5048
      Location:208 → 402
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:252 → 272
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_039078917.2 → XP_038934845.1  zinc finger protein 641 isoform X3

      Conserved Domains (3) summary
      smart00349
      Location:34 → 95
      KRAB; krueppel associated box
      COG5048
      Location:147 → 341
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:191 → 211
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_039078918.2 → XP_038934846.1  zinc finger protein 641 isoform X4

      Conserved Domains (3) summary
      smart00349
      Location:29 → 81
      KRAB; krueppel associated box
      COG5048
      Location:133 → 327
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:177 → 197
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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