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    Adgrg7 adhesion G protein-coupled receptor G7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 304014, updated on 9-Dec-2024

    Summary

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    Symbol
    Adgrg7provided by RGD
    Full Name
    adhesion G protein-coupled receptor G7provided by RGD
    Primary source
    RGD:1307217
    See related
    EnsemblRapid:ENSRNOG00000001634 AllianceGenome:RGD:1307217
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gpr128
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human ADGRG7 (adhesion G protein-coupled receptor G7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 9.9), Uterus (RPKM 6.0) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Adgrg7 in Genome Data Viewer
    Location:
    11q12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (57282904..57345417)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (43808101..43877539)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (46103173..46172303)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A like 9, pseudogene 1 Neighboring gene ubiquitin-ribosomal protein eS31 fusion protein-like Neighboring gene transmembrane protein 45A Neighboring gene ribosomal protein S27a, pseudogene 21 Neighboring gene uncharacterized LOC134481066 Neighboring gene trafficking from ER to golgi regulator Neighboring gene ABI family member 3 binding protein Neighboring gene uncharacterized LOC134481065

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    adhesion G-protein coupled receptor G7
    Names
    G protein-coupled receptor 128
    probable G-protein coupled receptor 128
    probable G-protein coupled receptor 128-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107098.1 → NP_001100568.1  adhesion G-protein coupled receptor G7

      See identical proteins and their annotated locations for NP_001100568.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473967
      UniProtKB/TrEMBL
      A6IQP0, D4AAI8
      Related
      ENSRNOP00000002232.5, ENSRNOT00000002232.7
      Conserved Domains (2) summary
      cd15257
      Location:428 → 727
      7tmB2_GPR128; orphan adhesion receptor GPR128, member of the class B2 family of seven-transmembrane G protein-coupled receptors
      pfam01825
      Location:378 → 418
      GPS; GPCR proteolysis site, GPS, motif

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      57282904..57345417
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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